2,4-Dichloropyridine-3-carboxaldehyde Chemical Properties

Melting point:

72-75℃

Boiling point:

261.8±35.0 °C(Predicted)

Density 

1.488±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

form 

powder to crystal

pka

-1.17±0.10(Predicted)

color 

White to Orange to Green

Sensitive 

Air Sensitive

InChIKey

GWBHJHIZHNTJLA-UHFFFAOYSA-N

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38

Safety Statements 

26

RIDADR 

UN 2811 6.1 / PGIII

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2933399990

2,4-Dichloropyridine-3-carboxaldehyde Usage And Synthesis

Chemical Properties

Yellow solid

Synthesis

To a solution of 2,4-dichloropyridine (2 g, 13.51 mmol) in tetrahydrofuran (20 mL) at -78° C added LDA in THF/heptane/ethylbenzene (2M, 8.11 mL, 16.22 mmol) and the solution was stirred for 30 min. DMF (10.46 mL, 135 mmol) was added and the solution was stirred for 1 h and then warmed RT. The reaction mixture was quenched with saturated NH4Cl solution and diluted with ethyl acetate (50 mL). The organic layer was washed with saturated NaHCO3 (2*10 mL), water (20 mL), dried over Na2SO4, and concentrated under reduced pressure to afford 2,4-dichloronicotinaldehyde (2 g, 11.36 mmol, 84% yield). 

2,4-Dichloropyridine-3-carboxaldehyde(134031-24-6)Related Product Information

• 4-Dimethylaminopyridine
• 2,4-Dichloropyridine
• Quinclorac
• Dichloroacetic acid
• Clopyralid
• N,N-Dimethylacetamide
• Dichlorodimethylsilane
• 2-Chloro-5-chloromethylpyridine
• 3-Aminopyridine
• 3,4-Dichloropyridine
• 2,4-Dichlorobenzoic acid
• Thionyl chloride
• Sodium dichloroisocyanurate
• Dichloroethane
• ETHYL 2,4-DICHLORO-6-METHYLPYRIDINE-3-CARBOXYLATE
• 2,4-Dichloropyridine-3-carboxylic acid
• 5,6-Dichloropyridine-3-carboxaldehyde
• 2,6-Dichloropyridine-4-carboxaldehyde ,98%,2,6-DICHLOROPYRIDINE-4-CARBOXALDEHYDE