safracin B Chemical Properties

Boiling point:

755.1±60.0 °C(Predicted)

Density 

1.41±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Soluble in DMSO (up to 20 mg/ml)

pka

9.75±0.70(Predicted)

form 

solid

color 

Yellow-green

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

safracin B Usage And Synthesis

Description

Safracin B (87578-99-2) is a novel antibiotic of the saframycin family produced by?Pseudomonas fluorescens.1?Safracin B displays antitumor activity against L1210 and P388 leukemias and B16 melanoma. Compared with safracin A, the toxic and effective doses were much lower. Safracin B also prolonged the life of tumor-bearing mice to a greater extent than safracin A.2

Uses

Safracin B is a new antibiotics from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B is an antibiotic that exhibits anti-tumor properties.

References

1) Ikeda?et al.?(1983),?Safracins, new antitumor antibiotics. I. Producing organism, fermentation and isolation; J. Antibiot. Tokyo,?36?1279 2) Okumoto?et al. (1985),?Activity of safracins A and B, heterocyclic quinone antibiotics, on experimental tumors in mice; J. Antibiot.Tokyo,?38?767

safracin B(87578-99-2)Related Product Information

• Sunitinib Malate
• Cantharidin
• 2-(4-METHOXY-PHENYL)-PIPERAZINE
• 2,6-DIMETHYLBENZOQUINONE
• 1-METHYL-3-PHENYLPIPERAZINE
• 1-Methy-2-phenylpiperazine
• 3-(2-Piperazino)phenol, 95%
• TRIMETHYLQUINONE
• 4-PIPERAZINE-2-YL-PHENOL
• 5-methyl-1,2,3,4-tetrahydroisoquinoline
• mebeverine alcohol
• safracin B
• N1,N1-DIMETHYL-1-(3-METHYLPHENYL)-1,2-ETHANEDIAMINE
• (S)-1-ISOPROPYL-2-METHYL-PIPERAZINE
• OTAVA-BB 1148768
• 2-METHOXY-3-METHYL-[1,4]BENZOQUINONE
• 3(S)-AMINOMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE
• [2-AMINO-1-(4-METHOXYPHENYL)ETHYL]DIMETHYLAMINE