CAFTARIC ACID Chemical Properties

Melting point:

124～125℃

Boiling point:

618.2±55.0 °C(Predicted)

Density 

1.694±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,2-8°C

solubility 

Methanol (Slightly), Water (Slightly, Heated, Sonicated)

pka

2.18±0.25(Predicted)

color 

White to Pale Beige

Odor

at 100.00?%. odorless

Stability:

Hygroscopic

LogP

1.147 (est)

Safety Information

WGK Germany 

3

HS Code 

2918290000

CAFTARIC ACID Usage And Synthesis

Description

Caftaric acid is a phenolic acid and a tartaric acid ester form of caffeic acid . It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) free radicals in a cell-free assay (EC₅₀ = 20.4 μM) and inhibits oxidation of LDL isolated from human plasma by 97.6% compared to vehicle control in vitro when used at a concentration of 5 μM. Caftaric acid is the main phenolic compound in V. vinifera white, pink, and black table grapes as well as various wines. In vivo, caftaric acid content in dietary-administered red wine positively correlates with inhibition of protein carbonylation and decreased superoxide dismutase (SOD), glutathione peroxidase (Gpx), and catalase activities in mice.

Uses

Caftaric Acid is used in cancer therapy as an anticancer drug. Affecting the up regulation or down regulation of drug transporters or cytochrome p450 enzymes. Also provides antioxidant effects, found in wines.

Definition

ChEBI: Caftaric acid is a hydroxycinnamic acid.

target

LDL | NO

CAFTARIC ACID(67879-58-7)Related Product Information

• 1-Caffeoylquinic acid
• Cynarin
• 1,3,5-Tricaffeoylquinic acid
• Cryptochlorogenic acid
• Chlorogenic acid
• CYNARIN
• Cichoric acid
• ECHINACEA HERB P.E.
• 2,3,4,5-Tetracaffeoyl-D-Glucaric acid
• Isochlorogenic acid A
• Metoprolol tartrate
• L(+)-Tartaric acid
• 2-Carboxyethyl acrylate
• ChicoricAcid
• CAFTARIC ACID
• CAFTARIC ACID(AHP)
• CAFTARIC ACID(SH)
• Caftaric acid o-quinone