7-HYDROXYBENZO(A)PYRENE Chemical Properties

Melting point:

218.5°C

Boiling point:

371.47°C (rough estimate)

Density 

1.0921 (rough estimate)

refractive index 

1.6220 (estimate)

storage temp. 

Refrigerator

solubility 

Dichlorormethane (Slightly), DMSO (Slightly)

form 

Solid

pka

9.40±0.30(Predicted)

color 

Yellow plates from C6H6/pet ether

Safety Information

Toxicity

mmo-sat 16 mg/plate MUREAV 36,379,76

7-HYDROXYBENZO(A)PYRENE Usage And Synthesis

Uses

7-Hydroxybenzo[a]pyrene is a metabolite of Benzopyrene (BaP), a carcinogenic component of tobacco smoke implicated in lung cancer.

Definition

ChEBI: 7-Hydroxybenzo[a]pyrene is an ortho- and peri-fused polycyclic arene.

Synthesis Reference(s)

The Journal of Organic Chemistry, 46, p. 4157, 1981 DOI: 10.1021/jo00334a010

Safety Profile

Questionable carcinogen withexperimental tumorigenic and neoplastigenic data by skincontact. Human mutation data reported. When heated todecomposition it emits acrid smoke and fumes.

7-HYDROXYBENZO(A)PYRENE(37994-82-4)Related Product Information

• Benzopyrene Related Compound 7 (Benzo[a]pyrene-3, 6- Quinone)
• trans-Benzo[a]pyrene-4,5-dihydrodiol
• BENZO[A]PYRENE-D12
• Benzo(A)pyrene-1,6-dione, radical ion(1-)
• benzo(a)pyrene 7,8-dihydrodiol
• Benzopyrene Related Compound 6 ((3aS,4R,9bR)-4-(6-Bromo-1,3-Benzodioxol-5-yl)-3a,4,5,9b-Tetrahydro-3H-Cyclopenta-[c]-Qui
• benzo(a)pyrene 7,8-oxide
• Benzopyrene Related Compound 9
• 6,12-Benzo(a)pyrenedione
• Benzopyrene Related Compound (Mixture of Benzopyrene Related Compound 7 and 8)
• 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
• benzo(a)pyrene-7,8-dione
• BENZO(A)PYRENE-7,8-DIOL
• Benzo[a]pyrene
• 1-HYDROXYCHRYSENE
• 7-HYDROXYBENZO(A)PYRENE