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FRAXINOL

Basic information Safety Supplier Related

FRAXINOL Basic information

Product Name:
FRAXINOL
Synonyms:
  • FRAXINOL
  • 5,7-Dimethoxy-6-hydroxycoumarin
  • 6-Hydroxy-5,7-dimethoxy-2H-1-benzopyran-2-one
  • 6-Hydroxy-5,7-dimethoxycoumarin
  • Fraxil
  • 6-Hydroxy-5,7-dimethoxy-chromen-2-one
  • 6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one
  • 2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy-
CAS:
486-28-2
MF:
C11H10O5
MW:
222.19
Mol File:
486-28-2.mol
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FRAXINOL Chemical Properties

Melting point:
170-172℃
Boiling point:
449.7±45.0 °C(Predicted)
Density 
1.358
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO and methanol;
pka
8.95±0.20(Predicted)
form 
powder
color 
White-yellowish
Water Solubility 
slightly soluble in water
CAS DataBase Reference
486-28-2
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FRAXINOL Usage And Synthesis

Description

Fraxinol is a coumarin originally isolated from Ash tree bark. It inhibits growth of GLC-4 small cell lung carcinoma and COLO 320 colorectal cancer cells (IC50s = 193 and 165 μM, respectively). Fraxinol potentiates barbiturate-induced sleep in rats and rabbits.

FRAXINOLSupplier

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