3-methylcyclobutane-1-carboxylic acid Chemical Properties

Boiling point:

194℃

Density 

1.105

Flash point:

88℃

storage temp. 

Sealed in dry,Room Temperature

pka

4.81±0.40(Predicted)

Appearance

Colorless to light yellow Liquid

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36-52

Safety Statements 

26

RIDADR 

3265

HazardClass 

8

PackingGroup 

Ⅲ

HS Code 

2916200090

3-methylcyclobutane-1-carboxylic acid Usage And Synthesis

Uses

3-Methylcyclobutanecarboxylic acid is a reactant used in the preparation of alternating copolymers via. ring-opening metathesis polymerization (ROMP) of methylcyclobutene and dimethylcyclobutene.

Synthesis

General procedure for the synthesis of 3-methylenecyclobutanecarboxylic acid from 3-methylenecyclobutanecarboxylic acid: 3-methylenecyclobutanecarboxylic acid (1 g) was mixed with Pd/C catalyst (0.19 g) in methanol (20 mL) and the reaction was stirred overnight at room temperature in a hydrogen atmosphere (H2 balloon). Upon completion of the reaction, the mixture was filtered to remove the catalyst and the filtrate was concentrated under vacuum to give the target product 3-methylcyclobutyric acid (760 mg). Mass spectrometry analysis (ESI): calculated mass of C6H10O2 was 114; no corresponding mass was detected.

References

[1] Patent: WO2015/180613, 2015, A1. Location in patent: Page/Page column 20

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