4-(2-Chloroethyl)morpholine hydrochloride Chemical Properties

Melting point:

180-185 °C (dec.)(lit.)

storage temp. 

Store below +30°C.

solubility 

Chloroform (Slightly, Heated), Methanol (Slightly), Water (Slightly)

form 

Hygroscopic Crystalline Powder

color 

White to beige

PH

4.5-5 (10g/l, H2O, 20℃)

Water Solubility 

soluble

Sensitive 

Hygroscopic

BRN 

3684083

InChI

InChI=1S/C6H12ClNO.ClH/c7-1-2-8-3-5-9-6-4-8;/h1-6H2;1H

InChIKey

NBJHDLKSWUDGJG-UHFFFAOYSA-N

SMILES

C1OCCN(CCCl)C1.[H]Cl

CAS DataBase Reference

3647-69-6(CAS DataBase Reference)

EPA Substance Registry System

Morpholine, 4-(2-chloroethyl)-, hydrochloride (3647-69-6)

Safety Information

Hazard Codes 

T

Risk Statements 

21-25-34-43-52/53

Safety Statements 

26-36/37/39-45-61

RIDADR 

UN 2923 8/PG 3

WGK Germany 

2

RTECS 

QE0260000

Autoignition Temperature

365 °C

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29349990

Toxicity

LD50 orally in Rabbit: 96 mg/kg LD50 dermal Rat 1502 mg/kg

MSDS

• Language:English Provider:2-Morpholinoethyl chloride hydrochloride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-(2-Chloroethyl)morpholine hydrochloride Usage And Synthesis

Chemical Properties

White to beige crystalline powder

Uses

4-(2-Chloroethyl)morpholine hydrochloride (MOC) is used as intermediate for the synthesis of pharmaceuticals (e.g. floredil, morinamide, nimorazole and pholcodine). It is also used as Agrochemical Intermediates, dyestuff Intermediates.

Uses

4-(2-Chloroethyl)morpholine is used in the preparation of potential DNA cross-linking antitumor agents as well as synthetic opiate analogues. 4-(2-Chloroethyl)morpholine may possess sickle-cell hemogl obin aggregation inhibiting-activity.

Safety Profile

Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cland NOx.

4-(2-Chloroethyl)morpholine hydrochloride(3647-69-6)Related Product Information

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