PROSTAGLANDIN B2 Chemical Properties

Boiling point:

537.0±50.0 °C(Predicted)

Density 

1.118±0.06 g/cm3(Predicted)

Flash point:

-9 °C

storage temp. 

−20°C

solubility 

ethanol: ~100 mg/mL

form 

solution

pka

4.74±0.10(Predicted)

BRN 

2153006

Safety Information

Hazard Codes 

Xn,Xi,F

Risk Statements 

20/21/22-67-66-36-11

Safety Statements 

36/37-26-16

RIDADR 

UN 1231 3/PG 2

WGK Germany 

3

F 

8-10

MSDS

• Language:English Provider:SigmaAldrich

PROSTAGLANDIN B2 Usage And Synthesis

Description

Prostaglandin B₂ (PGB₂) is a non-enzymatic dehydration product resulting from the treatment of PGE₂ or PGA₂ (Item Nos. 10210 | 10007199) with strong base. It has weak agonist activity on TP receptors and can increase pulmonary blood pressure in the rabbit at relatively high doses (5 μg/kg).

PGB₂ MaxSpec^® standard is a quantitative grade standard of PGB₂ that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This PGB₂ MaxSpec^® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.

Uses

PGB2 (Prostaglandin B2) is an abundant prostaglandin released from osteoblasts.

Definition

ChEBI: Prostaglandin B2 is a prostaglandins B. It has a role as a human metabolite. It is a conjugate acid of a prostaglandin B2(1-).

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