Ponesterone A Chemical Properties

Melting point:

259-260° (dec)

alpha 

D15 +90° (methanol)

Boiling point:

640.5±55.0 °C(Predicted)

Density 

1.22±0.1 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

Methanol (Slightly, Sonicated), Pyridine (Slightly)

pka

14.13±0.70(Predicted)

form 

White to off-white powder.

color 

White to Off-White

InChIKey

PJYYBCXMCWDUAZ-JJJZTNILSA-N

CAS DataBase Reference

13408-56-5(CAS DataBase Reference)

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

Ponesterone A Usage And Synthesis

Description

Ponesterone A, a steroidal compound, falls under the category of ecdysone and can be found in various sources throughout nature. It was first isolated from insect plants by Nakanishi and Horm in 1966. Compared to β-ecdysone, Ponesterone proves to be 3-100 times more potent in specific neurosensory systems.

Uses

Ponasterone A has been used to induce the expression of human huntingtin (HTT).

Definition

ChEBI: Ponasterone A is a 2beta-hydroxy steroid, a 3beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 20-hydroxy steroid, a 22-hydroxy steroid, a 6-oxo steroid and a phytoecdysteroid.

Biochem/physiol Actions

Ponasterone A is an analogue of ecdysone. It induced death of non-adapted insects may be related to PoA regulating different set of genes when compared to 20E.

storage

+4°C

Ponesterone A(13408-56-5)Related Product Information

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