Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate Chemical Properties

Boiling point:

368.6±42.0 °C(Predicted)

Density 

1.154

refractive index 

1.544

storage temp. 

2-8°C

pka

10.85±0.20(Predicted)

InChI

InChI=1S/C15H19NO3/c1-2-19-15(18)13-8-9-16(11-14(13)17)10-12-6-4-3-5-7-12/h3-7,13H,2,8-11H2,1H3

InChIKey

JYFGIESQUYQLGM-UHFFFAOYSA-N

SMILES

N1(CC2=CC=CC=C2)CCC(C(OCC)=O)C(=O)C1

LogP

1.680 (est)

Safety Information

HazardClass 

IRRITANT

HS Code 

2933399990

Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate Usage And Synthesis

Uses

The microbial reduction of ethyl 1-benzyl-3-oxopiperidine-4-carboxylate could be used to make the ethyl cis-(3R,4R)-1-benzyl-3R-hydroxypiperidine-4R-carboxylate in high diastereomeric and enantiomeric excess[1].

References

[1] Zhiwei Guo. “Stereospecific microbial reduction of ethyl 1-benzyl-3-oxo-piperidine-4-carboxylate.” Tetrahedron, asymmetry 17 13 (2006): Pages 2015-2020.

Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate(39514-19-7)Related Product Information

• Methyl N-methyl piperidine-4-carboxylate
• Ethyl 1-methyl-4-piperidinecarboxylate
• 3-Piperidinone
• Ethyl N-benzyl-3-oxo-4-piperidine-carboxylate hydrochloride
• 4-Pyridylcarbinol
• 1-METHYLPIPERIDINE-4-CARBALDEHYDE
• 4-(ETHOXYMETHYL)PIPERIDINE
• 4-(METHOXYMETHYL)PIPERIDINE
• (1-Benzyl-4-piperidyl)methanol
• Piperidine-4-carbaldehyde
• Isonipecotic acid
• 1-Benzyl-3-piperidone
• 1-BENZYL-3-OXO-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
• 1-METHYL-PIPERIDINE-4-CARBOXYLIC ACID
• Ethyl 1-benzylpiperidine-4-carboxylate
• N-Benzylpiperidine-4-carboxaldehyde
• 1-Methyl-4-piperidinemethanol
• METHYL 1-BENZYLPIPERIDINE-4-CARBOXYLATE