3-Amino-4,6-dimethylpyridine Chemical Properties

Melting point:

68 °C

Boiling point:

255-257 °C

Density 

1.039±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

DMSO: 24 mg/mL (196.45 mM);Ethanol: 24 mg/mL (196.45 mM)

pka

7.54±0.18(Predicted)

Water Solubility 

Water: 24 mg/mL (196.45 mM)

CAS DataBase Reference

1193-71-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Hazard Note 

Irritant

HS Code 

2933399990

3-Amino-4,6-dimethylpyridine Usage And Synthesis

Uses

3-Amino-4,6-dimethylpyridine is a potent inhibitor of quinolines and thiazolopyridines. It has been shown to be an allosteric inhibitor of cellular quinoline and thiazolopyridine metabolism which leads to its high potency in cells. 3-Amino-4,6-dimethylpyridine selectively inhibits the activity of these enzymes without affecting other metabolic pathways. Oral dosing results in rapid absorption and a half life of about 2 hours.

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