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Acriflavine hydrochloride

Basic information Safety Supplier Related

Acriflavine hydrochloride Basic information

Product Name:
Acriflavine hydrochloride
Synonyms:
  • LISTERIA SELECTIVE SUPPLEMENT UVM-II
  • LISTERIA PALCAM SELECTIVE SUPPLEMENT
  • EUFLAVINE
  • EUFLAVIN HYDROCHLORIDE
  • CI 46000
  • Acriflavine DiHCl (Mixture of AcriflaviniuM Chloride with Proflavine)
  • Acriflavine hydrochloride, 98.5%
  • Acrifiavine Hcl
CAS:
8063-24-9
MF:
C27H28Cl4N6
MW:
578.36
EINECS:
1312995-182-4
Product Categories:
  • 8063-24-9
Mol File:
8063-24-9.mol
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Acriflavine hydrochloride Chemical Properties

Melting point:
260 °C
storage temp. 
+2°C TO
solubility 
H2O: soluble1mg/mL
form 
Powder
color 
Red-brown
PH Range
2
Water Solubility 
Soluble in water, dimethyl sulfoxide and methanol.
Merck 
123
BRN 
6265525
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
VWXAJKFSYJFBIW-UHFFFAOYSA-N
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Safety Information

Hazard Codes 
N-Xn,N,Xn
Risk Statements 
51/53-41-22-20/21/22
Safety Statements 
61-39-29-26-36
RIDADR 
UN 3077 9/PG 3
WGK Germany 
2
HazardClass 
9
PackingGroup 
III
HS Code 
38249064

MSDS

  • Language:English Provider:ACROS
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Acriflavine hydrochloride Usage And Synthesis

Chemical Properties

reddish-brown crystalline powder

Uses

Acriflavine Hydrochloride acts as an intercalating dye and also reported to inhibit mitochondriogenesis. It is an antiseptic and has been used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously.

Uses

Acriflavine is an topical antiseptic agent and has also been used for the treatment of external fungal infections.

Purification Methods

Purify it by dissolving in 50 parts of H2O, shaking with a small excess of freshly precipitated and washed Ag2O. The mixture is set aside overnight at 0o and filtered. The cake is not washed. The pH of the filtrate is adjusted to 7.0 with HCl and evaporated to dryness. The residue is then crystallised twice from MeOH, twice from H2O and dried at 120o. at 452nm has a log value of 4.67. Itis ared max powder which readily absorbs H2O. The solubility is increased in the presence of proflavin. The dihydrochloride is a deep red crystalline powder. It is available as a mixture of 3,6-diaminoacridinium chloride (35%) and its 10-metho-chloride (65%). [See Albert, The Acridines Arnold Press p 346 1966, Benda Chem Ber 45 1787 1912]. [Beilstein 23 I 650.]

Acriflavine hydrochlorideSupplier

Shanghai Gukang Biotechnology Co., LTD Gold
Tel
13564510648
Email
info@kanghaopharm.com
Changzhou Jia Ling Pharmaceutical Co. Ltd. (Changzhou City Animal Drugs Plant) Gold
Tel
0519-82553288
Wuhan Juchengyuan Biotechnology Co., Ltd Gold
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400-027-6007 18062142210
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804180422@qq.com
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
Email
market03@meryer.com