BOC-7-AMINO-HEPTANOIC ACID Chemical Properties

Melting point:

56-60 °C

Boiling point:

393.1±25.0 °C(Predicted)

Density 

1.050±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

soluble in Methanol

form 

powder to crystaline

pka

4.77±0.10(Predicted)

color 

White to Almost white

BRN 

2050867

CAS DataBase Reference

60142-89-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

WGK Germany 

3

F 

9-21

HS Code 

2922.50.5000

HazardClass 

IRRITANT

MSDS

• Language:English Provider:SigmaAldrich

BOC-7-AMINO-HEPTANOIC ACID Usage And Synthesis

Description

Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

BOC-7-AMINO-HEPTANOIC ACID(60142-89-4)Related Product Information

• BOC-7-AMINO-HEPTANOIC ACID
• N-Boc-2-piperidineacetic acid
• 3-(2-Carboxyethyl)piperidine-1-carboxylic acid tert-butyl ester
• BOC-1,2-CIS-ACHC-OH
• BOC-1,2-TRANS-ACHC-OH
• 7-Aminoheptanoic acid
• BOC-ASU-OH
• FMOC-L-BETA-HOMOLYSINE(BOC)
• BOC-D-2-AMINOSUBERIC ACID
• FMOC-L-HOLYS(BOC)-OH
• N-A-CBZ-(2-N-BOC-PIPERIDINYL) GLYCINE
• FMOC-D, L-HOMO[ALA-4-PIP(N-BOC)]
• FMOC-D, L-CIS/TRANS-CHA(4-NH-BOC)
• 2-METHOXYCARBONYLMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• FMOC-L-CIS/TRANS-CHA(4-NH-BOC)
• (S)-A-FMOC-G-BOC-4-HOMO-PIPERIDYLALANINE
• (2S,4S)-N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N'-T-BUTYLOXYCARBONYL-2-PYRROLIDINYLALANINE
• FMOC-D, L-ALA(3-PYRROLIDINYL-(2-N-BOC))