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BOC-7-AMINO-HEPTANOIC ACID

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BOC-7-AMINO-HEPTANOIC ACID Basic information

Product Name:
BOC-7-AMINO-HEPTANOIC ACID
Synonyms:
  • BOC-AHEPT-OH
  • BOC-7-AHP-OH
  • BOC-7-AMINO-HEPTANOIC ACID
  • BOC-NH-(CH2)6-COOH
  • N-TERT-BUTYLOXYCARBONYL-7-AMINOHEPTANOIC ACID
  • 7-(BOC-AMINO)ENANTHIC ACID
  • 7-(BOC-AMINO)HEPTANOIC ACID
  • 7-amino-2-[(2-methylpropan-2-yl)oxy-oxomethyl]heptanoic acid
CAS:
60142-89-4
MF:
C12H23NO4
MW:
245.32
Product Categories:
  • Unusual amino acids
Mol File:
60142-89-4.mol
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BOC-7-AMINO-HEPTANOIC ACID Chemical Properties

Melting point:
56-60 °C
Boiling point:
393.1±25.0 °C(Predicted)
Density 
1.050±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
soluble in Methanol
form 
powder to crystaline
pka
4.77±0.10(Predicted)
color 
White to Almost white
BRN 
2050867
CAS DataBase Reference
60142-89-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
WGK Germany 
3
9-21
HS Code 
2922.50.5000
HazardClass 
IRRITANT

MSDS

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BOC-7-AMINO-HEPTANOIC ACID Usage And Synthesis

Description

Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

BOC-7-AMINO-HEPTANOIC ACIDSupplier

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