ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > BOC-amino acid > 1-Boc-4-methylpiperidine-4-carboxylic acid
1-Boc-4-methylpiperidine-4-carboxylic acid
1-Boc-4-methylpiperidine-4-carboxylic acid Basic information
- Product Name:
- 1-Boc-4-methylpiperidine-4-carboxylic acid
- Synonyms:
-
- N-BOC-4-METHYL ISONIPECOTIC ACID
- N-BOC-4-METHYL-4-METHYLPIPERIDINECARBOXYLIC ACID
- N-BOC-4-METHYL-4-PIPERIDINECARBOXYLIC ACID
- CHEMBRDG-BB 4002933
- 4-METHYL-4-CARBOXY-1-N-BOC-PIPERIDINE
- 4-METHYL-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER
- 1-BOC-4-METHYL-PIPERIDINE-4-CARBOXYLIC ACID
- 1-Boc-4-methyl-4-piperidinecarboxylic Acid
- CAS:
- 189321-63-9
- MF:
- C12H21NO4
- MW:
- 243.3
- Product Categories:
-
- API intermediates
- Amino Acids and Derivatives
- Heterocycles
- Pyridines
- Mol File:
- 189321-63-9.mol
More
Less
1-Boc-4-methylpiperidine-4-carboxylic acid Chemical Properties
- Boiling point:
- 354.3±35.0 °C(Predicted)
- Density
- 1.129±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.69±0.20(Predicted)
- InChI
- InChI=1S/C12H21NO4/c1-11(2,3)17-10(16)13-7-5-12(4,6-8-13)9(14)15/h5-8H2,1-4H3,(H,14,15)
- InChIKey
- OKBNEDPOUYRYNP-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC(C)(C(O)=O)CC1
- CAS DataBase Reference
- 189321-63-9(CAS DataBase Reference)
More
Less
1-Boc-4-methylpiperidine-4-carboxylic acid Usage And Synthesis
Chemical Properties
White to Light yellow powder to crystal
Synthesis
A mixture of Ethyl N-Boc-4-methylpiperidine-4-carboxylate (4.1 g, 15.1mmol) and lithium hydroxide (2.17g, 90.6mmol) in methanol (3OmL)ZH2O (2OmL) was stirred at a temperature of about 25 ℃ for 16h. After evaporation to dryness, the residue was partitioned between DCM and brine. The organic layer was separated, dried (MgSO4), filtered, and concentrated under reduced pressure to provide 3.38g of 1-Boc-4-methylpiperidine-4-carboxylic acid as a white solid (yield 92.0 percent).
1-Boc-4-methylpiperidine-4-carboxylic acid Preparation Products And Raw materials
Raw materials
1-Boc-4-methylpiperidine-4-carboxylic acidSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
ITIC MEDCHEM(SUZHOU) CO.,LTD.
- Tel
- 0512-68323967 18015559028
- sales@iticmedchem.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
Wuhan Chemwish Technology Co., Ltd
- Tel
- 86-027-67849912
- sales@chemwish.com
Capot Chemical Co., Ltd
- Tel
- +86 (0) 571 85 58 67 18
- sales@capotchem.com
More
Less
1-Boc-4-methylpiperidine-4-carboxylic acid(189321-63-9)Related Product Information
- o-Toluic acid
- p-Toluic acid
- Triacetonediamine
- 2,2,6,6-Tetramethyl-4-piperidinol
- tert-Butyl carbazate
- 1,2,2,6,6-Pentamethyl-4-piperidinol
- Isonipecotic acid
- BOC-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID
- 1-BOC-4-ETHYL-4-PIPERIDINECARBOXYLIC ACID
- Ethyl N-Boc-4-methylpiperidine-4-carboxylate
- N-Boc-3-Methylnipecotic acid ethyl ester
- 1-N-Boc-3-Methylpiperidine-3-carboxylic acid
- BOC-4-CYCLOHEXYL-PIPERIDINE-4-CARBOXYLIC ACID
- N-BOC-4-(P-FLUOROPHENYL)-4-PIPERIDINECARBOXYLIC ACID
- 1,4-Piperidinedicarboxylic acid, 4-(2-propen-1-yl)-, 1-(1,1-dimethylethyl) ester
- METHYL 4-AMINOMETHYL-1-BOC-PIPERIDINE-4-CARBOXYLATE
- N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC ACID
- N-BOC-4-(P-CHLOROPHENYL)-4-PIPERIDINE CARBOXYLIC ACID