3,3-Diethoxypropionitrile Chemical Properties

Melting point:

82-84

Boiling point:

91-93 °C/11 mmHg (lit.)

Density 

0.954 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.415(lit.)

Flash point:

183 °F

storage temp. 

Inert atmosphere,2-8°C

solubility 

32g/l

form 

Oil

color 

Clear Colourless to Pale Yellow

InChI

InChI=1S/C7H13NO2/c1-3-9-7(5-6-8)10-4-2/h7H,3-5H2,1-2H3

InChIKey

WBOXEOCWOCJQNK-UHFFFAOYSA-N

SMILES

C(#N)CC(OCC)OCC

CAS DataBase Reference

2032-34-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

3275

WGK Germany 

2

Hazard Note 

Irritant

HS Code 

29269095

MSDS

• Language:English Provider:1,1-Diethoxy-2-cyanoethane
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3,3-Diethoxypropionitrile Usage And Synthesis

Chemical Properties

CLEAR YELLOW TO BROWNISH LIQUID

Uses

3,3-Diethoxypropionitrile may be used in the synthesis of 2-(2,2-diethoxy-ethyl)-pyridine, via [2+2+2]-cycloaddition reaction. It may be used in the synthesis of cyanomalondialdehyde.

Uses

3,3-Diethoxypropionitrile is a propionitrile derivative used in the preparation of various biologically active compounds such as p38α mitogen-activated protein kinase inhibitors.

Synthesis Reference(s)

Journal of the American Chemical Society, 69, p. 2657, 1947 DOI: 10.1021/ja01203a028

General Description

3,3-Diethoxypropionitrile is a cyanide derivative. It undergoes reaction with urea in refluxing butanolic sodium butoxide to afford 4-amino-2(1H)-pyrimidinone and cytosine. Its physical properties (density, refractive index, boiling point and melting point) have been reported.

3,3-Diethoxypropionitrile(2032-34-0)Related Product Information

• Bromoacetaldehyde dimethyl acetal
• Bromoacetaldehyde diethyl acetal
• Ethoxyquin
• Aminoacetaldehyde dimethyl acetal
• Decabromodiphenyl Ethane
• Chloroacetaldehyde dimethyl acetal
• 3-Hydroxypropionitrile
• Chloroacetaldehyde diethyl acetal
• Diethoxymethyl acetate
• polyvinyl formal-acetal
• DIETHOXYMETHANE
• 3,3-Dimethoxypropanenitrile
• 3-Ethoxypropionitrile
• 2,2'-DIETHOXYPROPIONITRILE,2,2-DIETHOXYPROPIONITRILE
• 3,3-Diethoxypropionitrile
• polyvinyl acetaldehyde
• 3,3-DIETHOXY-2-(ETHOXYMETHYL)PROPANENITRILE