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(Z)-4-HYDROXYTAMOXIFEN

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(Z)-4-HYDROXYTAMOXIFEN Basic information

Product Name:
(Z)-4-HYDROXYTAMOXIFEN
Synonyms:
  • 4-OH-TAM
  • TAMOXIFEN, (Z)-4-HYDROXY-
  • TAMOXIFEN, 4-HYDROXY-, (Z)-
  • (Z)-4-HYDROXYTAMOXIFEN
  • (Z)-4-[1-[4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL]-2-PHENYL-1-BUTENYL-PHENOL
  • (Z)-4-[1-(P-(DIMETHYLAMINOETHOXY)PHENYL)-2-PHENYL-1-BUTENYL]PHENOL
  • [Z]-1-[P-DIMETHYLAMINOETHOXYPHENYL]-1,2-DIPHENYL-1-BUTEN-4-OL
  • Phenol, 4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenyl-1-butenyl)-, (Z)-
CAS:
65213-48-1
MF:
C26H29NO2
MW:
387.51
Mol File:
65213-48-1.mol
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(Z)-4-HYDROXYTAMOXIFEN Chemical Properties

Melting point:
137 - 143°C
storage temp. 
2-8°C
solubility 
95% ethanol: 20 mg/mL
form 
powder
color 
white
Stability:
Light Sensitive
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Safety Information

Hazard Codes 
Xn
Risk Statements 
20/21/22-63
Safety Statements 
22-23-36
WGK Germany 
3
RTECS 
SL1210000

MSDS

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(Z)-4-HYDROXYTAMOXIFEN Usage And Synthesis

Uses

(Z)-4-Hydroxy Tamoxifen is a metabolite of Tamoxifen (T006000). (Z)-4-Hydroxy Tamoxifen is a hydroxylated analogue of Tamoxifen. (Z)-4-Hydroxy Tamoxifen is a metabolite of Tamoxifen with anti-estrogenic properties.

Definition

ChEBI: Afimoxifene is a tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen. It has a role as an antineoplastic agent, an estrogen receptor antagonist and a metabolite. It is a tertiary amino compound and a member of phenols. It is functionally related to a tamoxifen.

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