Bucladesine
Bucladesine Basic information
- Product Name:
- Bucladesine
- Synonyms:
-
- BUCLADESINE
- Dibutyryladenosine cyclic 3',5'-monophosphate
- Calciuml Dibutyryladenosine Cyclophosphate
- n-6,o-2'-dibutyryl adenosine cyclic 3':5'-monophosphate
- n-(9-beta-d-ribofuranosyl-9h-furin-6-yl)-butyramide cyclic 3',5'-(hydrogen phosphate) 2'-butyrate
- 3',5'-Cyclic AMP dibutyrate
- Cyclic AMP dibutyrate
- Dibutyryl 3',5'-Cyclic AMP
- CAS:
- 362-74-3
- MF:
- C18H24N5O8P
- MW:
- 469.39
- EINECS:
- 206-649-8
- Mol File:
- 362-74-3.mol
Bucladesine Chemical Properties
- Density
- 1.72±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO; Methano
- pka
- 0.82±0.60(Predicted)
- form
- Solid
- color
- White
Bucladesine Usage And Synthesis
Description
Bucladesine is a cyclic nucleotide derivative that mimics the action of endogenous CYCLIC AMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. (From Merck Index, 11th ed)
Uses
Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations. The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.
Definition
ChEBI: Bucladesine is a 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP. It has a role as an agonist, a vasodilator agent and a cardiotonic drug. It is a butyrate ester, a 3',5'-cyclic purine nucleotide and a member of butanamides. It is functionally related to a 3',5'-cyclic AMP.
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Bucladesine(362-74-3)Related Product Information
- Losartan potassium
- L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE
- Dibutyryl adenosine cyclophosphate calcium
- Pantoprazole
- Gastrodin
- Vinpocetine
- (S)-Amlodipine
- Ambroxol
- Oxiracetam
- Cyclic AMP
- S-Adenosyl-L-methionine
- N-ACETYLGLYCINAMIDE
- Creatine phosphate disodium salt
- Cephalosporin
- Bucladesine
- Bucladesine sodium
- N6,2'-O-DISUCCINYLADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, N6,O2'-DIOCTANOYL-, SODIUM SALT