phleomycin D1
phleomycin D1 Basic information
- Product Name:
- phleomycin D1
- Synonyms:
-
- ZEOCIN
- phleomycin D1
- (7R)-N1-[4-[[Amino(imino)methyl]amino]butyl]-7,8-dihydrobleomycinamide
- Bleomycinamide, N1-[4-[(aminoiminomethyl)amino]butyl]-7,8-dihydro-
- Zeocin (Phleomycin D1, zeomycin)
- ZEOCINE
- CAS:
- 11031-11-1
- MF:
- C55H86N20O21S2
- MW:
- 1427.52
- Product Categories:
-
- plantgrowth
- Mol File:
- 11031-11-1.mol
phleomycin D1 Chemical Properties
- Density
- 1.79±0.1 g/cm3(Predicted)
- solubility
- Fully miscible.
- pka
- 10.84±0.46(Predicted)
phleomycin D1 Usage And Synthesis
Uses
Zeocin is a DNA intercalating agent and a glycopeptide antibiotic. Zeocin is a related compound of Bleomycin (B595805), a glycopeptide antibiotic.
Definition
ChEBI: Phleomycin D1 is a glycopeptide originally isolated from the bacterium Streptomyces verticillus which contains a (4'R)-4',5'-dihydro-2,4'-bi-1,3-thiazole-2',4-diyl moiety with a a 4-guanidylbutylaminocarbonyl group attached to the 4-position of the terminal thiazole ring. Like all phleomycins, phleomycin D1 can form complexes with redox-active metals such as Co, Cu, and Fe. It has a role as an antineoplastic agent, an antifungal agent, an antimicrobial agent, an antibacterial agent and a bacterial metabolite. It is a chelate-forming peptide, a member of guanidines, a disaccharide derivative, a bi-1,3-thiazole and a glycopeptide.
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