STRYCHNINE HYDROCHLORIDE
STRYCHNINE HYDROCHLORIDE Basic information
- Product Name:
- STRYCHNINE HYDROCHLORIDE
- Synonyms:
-
- (4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline-14-one:hydrochloride
- Strychnidin-10-one hydrochloride (1:1)
- (4aR,4a1R,5aS,8aR,8a1S,15aS)-4a1,5,5a,7,8,8a1,15,15a-Octahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14(4aH)-one hydrochloride
- Strychnine Hydrochloride Hydrate
- STRYCHNINE HCL
- STRYCHNINE HYDROCHLORIDE
- Strychnidin-10-one, monohydrochloride (9ci)
- Strychnidin-10-onehydrochloride
- CAS:
- 1421-86-9
- MF:
- C21H23ClN2O2
- MW:
- 370.87
- EINECS:
- 215-826-9
- Product Categories:
-
- GABA and Glycine Receptor ModulatorsNeurotransmission
- Glycinergics
- chiral
- Ion Channels
- Ligand-Gated Ion Channels
- Neurotransmitters
- Alkaloids
- Biochemistry
- for Resolution of Acids
- Indole Alkaloids
- Optical Resolution
- Synthetic Organic Chemistry
- Mol File:
- 1421-86-9.mol
STRYCHNINE HYDROCHLORIDE Chemical Properties
- Melting point:
- 295 °C
- storage temp.
- Store at RT
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Sparingly, Slightly)
- form
- Solid
- color
- White to Light Beige
- Merck
- 14,8855
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 1421-86-9(CAS DataBase Reference)
- EPA Substance Registry System
- Strychnine hydrochloride (1421-86-9)
Safety Information
- Hazard Codes
- T+,N
- Risk Statements
- 26/27/28-51/53-50/53-26/28
- Safety Statements
- 22-36/37/39-45-61-60-28-13
- RIDADR
- UN 1692 6.1/PG 1
- WGK Germany
- 3
- RTECS
- WL2430000
- HazardClass
- 6.1(a)
- PackingGroup
- I
MSDS
- Language:English Provider:SigmaAldrich
STRYCHNINE HYDROCHLORIDE Usage And Synthesis
Uses
Strychnine hydrochloride has been used as a glycine receptor antagonist in the retina for biophysiological functions. It has also been used to block glutamatergic, GABAergic and glycinergic receptors and gap junctions.
Uses
Strychnine Hydrochloride acts as an antagonist for cholinesterases and beta amyloid aggregation.
Definition
ChEBI: A hydrochloride obtained by combining strychnine with one molar equivalent of hydrogen chloride.
Biological Activity
Competitive glycine receptor antagonist; convulsant. Also nicotinic receptor antagonist; displays competitive antagonism at α 7 receptors and non-competitive antagonism at α 4 β 2 receptors.
Biochem/physiol Actions
Strychnine is a potent convulsant, which is extracted from Strychnos nux vomica seeds. At high doses, the compound causes convulsions and ultimately death due to respiratory paralysis. Strychnine acts as a respiratory, circulatory and digestive stimulant.
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STRYCHNINE HYDROCHLORIDE(1421-86-9)Related Product Information
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