ChemicalBook > Product Catalog > API > Specialty drugs > Antidote > 1,1'-TRIMETHYLENE-BIS(4-FORMYLPYRIDINIUM BROMIDE) DIOXIME
1,1'-TRIMETHYLENE-BIS(4-FORMYLPYRIDINIUM BROMIDE) DIOXIME
1,1'-TRIMETHYLENE-BIS(4-FORMYLPYRIDINIUM BROMIDE) DIOXIME Basic information
- Product Name:
- 1,1'-TRIMETHYLENE-BIS(4-FORMYLPYRIDINIUM BROMIDE) DIOXIME
- Synonyms:
-
- TMB-4
- 1,1’-(1,3-propanediyl)bis(4-(hydroxyimino)methyl-pyridiniudibromide
- pyridinium,1,1’-trimethylenebis(4-formyl-,dibromide,dioxime
- tmb-4dibromide
- trimedoxime
- trimedoximebromide
- 1,1'-TRIMETHYLENE-BIS(4-FORMYLPYRIDINIUM BROMIDE) DIOXIME
- 1,1'-trimethylenebis(4-(hydroxyimino-methyl)pyrid
- CAS:
- 56-97-3
- MF:
- C15H18Br2N4O2
- MW:
- 446.14
- EINECS:
- 200-304-5
- Mol File:
- 56-97-3.mol
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1,1'-TRIMETHYLENE-BIS(4-FORMYLPYRIDINIUM BROMIDE) DIOXIME Chemical Properties
- Melting point:
- 231 °C (dec.)(lit.)
- storage temp.
- −20°C
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1,1'-TRIMETHYLENE-BIS(4-FORMYLPYRIDINIUM BROMIDE) DIOXIME Usage And Synthesis
Uses
Trimedoxime (TMB-4) is a potent reactivator of AChE. Trimedoxime shows potency in inducing oxidative stress, with the IC50 of 22 mM[1].
References
[1] Nela Váňová, et al. In Vitro Evaluation of Oxidative Stress Induced by Oxime Reactivators of Acetylcholinesterase in HepG2 Cells. 2023 Dec 18; 36(12): 1912–1920. DOI:10.1021/acs.chemrestox.3c00203
1,1'-TRIMETHYLENE-BIS(4-FORMYLPYRIDINIUM BROMIDE) DIOXIMESupplier
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