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N-Cbz-L-histidine

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N-Cbz-L-histidine Basic information

Product Name:
N-Cbz-L-histidine
Synonyms:
  • (S)-2-BENZYLOXYCARBONYLAMINO-3-(3H-IMIDAZOL-4-YL)-PROPIONIC ACID
  • N2-CARBOBENZYLOXY-L-HISTIDINE
  • N-ALPHA-Z-L-HISTIDINE
  • NALPHA-CARBOBENZOXY-L-HISTIDINE
  • N(ALPHA)-CBZ-L-HISTIDINE
  • N-ALPHA-CARBOBENZYLOXY-L-HISTIDINE
  • N-CARBOBENZOXY-L-HISTIDINE
  • N-ALPHA-BENZYLOXYCARBONYL-L-HISTIDINE
CAS:
14997-58-1
MF:
C14H15N3O4
MW:
289.29
EINECS:
239-084-0
Product Categories:
  • Amino Acid Derivatives
  • Histidine [His, H]
  • Z-Amino Acids and Derivatives
  • Cbz-Amino Acids
  • Amino Acids
  • Amino Acids (N-Protected)
  • Biochemistry
  • Z-Amino acid series
Mol File:
14997-58-1.mol
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N-Cbz-L-histidine Chemical Properties

Melting point:
168 °C (dec.)(lit.)
alpha 
-24 º (c=1 in 6 M HCl)
Boiling point:
616.7±55.0 °C(Predicted)
Density 
1.368±0.06 g/cm3(Predicted)
refractive index 
-23.5 ° (C=6, 6mol/L HCl)
storage temp. 
Sealed in dry,2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
3.35±0.10(Predicted)
form 
powder to crystal
color 
White to Almost white
optical activity
[α]20/D 24°, c = 1% in 6 M HCl
Water Solubility 
almost transparency
BRN 
3561682
InChIKey
WCOJOHPAKJFUDF-LBPRGKRZSA-N
CAS DataBase Reference
14997-58-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
HS Code 
29332900

MSDS

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N-Cbz-L-histidine Usage And Synthesis

Chemical Properties

White powder

Uses

Nα-Cbz-L-histidine is an N-Cbz-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle.

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