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α-Methyl-3,4-dihydroxy-L-phenylalanine methyl ester

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α-Methyl-3,4-dihydroxy-L-phenylalanine methyl ester Basic information

Product Name:
α-Methyl-3,4-dihydroxy-L-phenylalanine methyl ester
Synonyms:
  • (αS)-α-Amino-α-methyl-3,4-dihydroxybenzenepropionic acid methyl ester
  • 3-Hydroxy-α-methyl-L-tyrosine methyl ester
  • α-Methyl-3,4-dihydroxy-L-phenylalanine methyl ester
  • α-Methyl-3-hydroxy-L-tyrosine methyl ester
  • Carbidopa EP Impurity B
  • Carbidopa Impurity 2(Carbidopa EP Impurity B)
  • L-Tyrosine, 3-hydroxy-α-methyl-, methyl ester
  • α-Methyldopa Methyl Ester
CAS:
18181-08-3
MF:
C11H15NO4
MW:
225.24
Mol File:
18181-08-3.mol
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α-Methyl-3,4-dihydroxy-L-phenylalanine methyl ester Chemical Properties

storage temp. 
Refrigerator
solubility 
DMSO, Methanol (Slightly)
form 
Solid
Boiling point:
386.9±37.0 °C(Predicted)
Density 
1.280±0.06 g/cm3(Predicted)
Melting point:
165-166 °C
pka
9.82±0.10(Predicted)
color 
Yellow to Very Dark Brown
InChI
InChI=1/C11H15NO4/c1-11(12,10(15)16-2)6-7-3-4-8(13)9(14)5-7/h3-5,13-14H,6,12H2,1-2H3/t11-/s3
InChIKey
MKFJJXIMFTXSEM-LBPXTSNRNA-N
SMILES
C(OC)(=O)[C@](N)(C)CC1=CC=C(O)C(O)=C1 |&1:4,r|
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α-Methyl-3,4-dihydroxy-L-phenylalanine methyl ester Usage And Synthesis

Uses

α-Methyldopa Methyl Ester is an impurity in the synthesis of L-α-Methyl DOPA Methyl Ester Hydrochloride which is a Methyldopa angiotensin II analog.

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