n-Octyl-β-D-glucopyranoside Chemical Properties

Melting point:

105 °C

alpha 

-32 º (c=5, water)

Boiling point:

354.3°C (rough estimate)

Density 

1.0869 (rough estimate)

refractive index 

-27 ° (C=1, MeOH)

storage temp. 

-20°C

solubility 

DMSO (Slightly), Water (Slightly)

form 

Crystalline Powder and Chunks

pka

12.95±0.70(Predicted)

color 

White

Water Solubility 

3 g/10 mL

Sensitive 

Hygroscopic

Merck 

14,6767

BRN 

84118

Stability:

Hygroscopic

InChIKey

HEGSGKPQLMEBJL-QNOVJUQQSA-N

LogP

0.887 (est)

CAS DataBase Reference

29836-26-8(CAS DataBase Reference)

EPA Substance Registry System

Octyl .beta.-D-glucopyranoside (29836-26-8)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29400090

MSDS

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n-Octyl-β-D-glucopyranoside Usage And Synthesis

Description

n-Octyl-β-D-glucopyranoside is a non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. n-Octyl-β-D-glucopyranoside has a well–defined chemical structure, small uniform micelles, and high water solubility, which make n-Octyl-β-D-glucopyranoside superior to most other nonionic detergents for membrane solubilization. Because of the high critical micelle concentration (20-25 mM), n-Octyl-β-D-glucopyranoside has the additional advantage of being removed easily by dialysis when compared to bile salts. n-Octyl-β-D-glucopyranoside is also known as N-Octyl glucoside, OGP, OG, n-Octylglucoside, and octyl-β-D-glucopyranoside.

Chemical Properties

white crystalline powder and chunks

Uses

A nonionic detergent for the solubilization of membrane bound protein.

Uses

Unlike many other detergents, octyl glucoside is a pure, single compound of defined structure. Very effective for insulin binding and solubilization studies of membran

Uses

Detergent and surfactant for biological systems.

Definition

ChEBI: Octyl beta-D-glucopyranoside is an beta-D-glucoside in which the anomeric hydrogen of beta-D-glucopyranose is substituted by an octyl group. It has a role as a plant metabolite.

Purification Methods

Purify n-Octyl-β-D-glucopyranoside by recrystallisation from Me2CO. It is hygroscopic and should be stored in a well-stoppered container. [Noller & Rockwell J Am Chem Soc 6 0 2076 1938, Pigman & Richtmyer J Am Chem Soc 64 369 1942.] It is a UV transparent non-ionic dialysable detergent for solubilising membrane proteins. The D-isomer with [] D 20 +118o (c 1, MeOH) has similar solubilising properties. [Lazo & Quinn Anal Biochem 102 68 1980, Stubbs et al. Biochim Biophys Acta 426 46 1976, Beilstein 17/7 V 38.]

n-Octyl-β-D-glucopyranoside(29836-26-8)Related Product Information

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• N-DECYL-BETA-D-MALTOPYRANOSIDE
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• BETA-GLUCOSIDASE