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D-(-)-3-Acetylthio-2-methylpropionic acid

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D-(-)-3-Acetylthio-2-methylpropionic acid Basic information

Product Name:
D-(-)-3-Acetylthio-2-methylpropionic acid
Synonyms:
  • D(-)S-ACETYL-BETA-MERCAPTO ISOBUTYRIC ACID
  • D-(S)-3-ACETYL-3-MERCAPTO-2-METHYL PROPANOIC ACID
  • D-(-)-3-ACETYLSULFANYL-2-METHYLPROPIONIC ACID
  • d-(-)-3-acetylthio-2-methylpropionic acid
  • (S)-β-(Acetylmercapto)isobutyric acid
  • D-3-(Acetylthio)-2-methylpropanoic acid
  • D-(S)-3-Acetylthio-2-methylpropionic acid
  • (S)-(-)-3-(ACETYLTHIO)-2-METHYLPROPIONI&
CAS:
76497-39-7
MF:
C6H10O3S
MW:
162.21
EINECS:
278-480-8
Product Categories:
  • Carboxylic Acids (Chiral)
  • Chiral Building Blocks
  • Synthetic Organic Chemistry
Mol File:
76497-39-7.mol
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D-(-)-3-Acetylthio-2-methylpropionic acid Chemical Properties

Melting point:
5 °C
Boiling point:
120-132 °C (1 mmHg)
alpha 
-46 º (c=1, 96% EtOH)
Density 
1.178 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.490
Flash point:
>230 °F
storage temp. 
Store at 0-5°C
solubility 
Chloroform (Slightly), Ethanol (Sparingly), Methanol (Slightly)
form 
liquid
pka
4.22±0.10(Predicted)
Water Solubility 
INSOLUBLE
CAS DataBase Reference
76497-39-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C,T
Risk Statements 
34-36-24/25
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
HS Code 
29309070

MSDS

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D-(-)-3-Acetylthio-2-methylpropionic acid Usage And Synthesis

Chemical Properties

clear colourless to slightly yellow liquid

Uses

ACE-inhibitors.

Uses

S-Acetylthio-2-methylpropionic acid (S-AMPA) is a key chiral intermediate for Captopril (C175750) and other hypertension drugs.

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