Basic information Description Benefits Safety Supplier Related
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MK-677

Basic information Description Benefits Safety Supplier Related

MK-677 Basic information

Product Name:
MK-677
Synonyms:
  • 2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate
  • MK677(Ibutamoren Mesylate)
  • MK-677; CRESCENDO; MK 0677; MK-0677; MK0677;MK677;MK 677
  • CS-1402
  • MK677 MK 677 IBUTAMOREN
  • mk677 mk 677 Ibutamoren,whnohe_lucy(at)163.com
  • MK677,Mk677
  • MK-677 Selective Androgen Receptor Modulators SARMs Bodybuilding CAS 159752-10-0
CAS:
159752-10-0
MF:
C28H40N4O8S2
MW:
624.77
EINECS:
1308068-626-2
Product Categories:
  • SARMs(Selective androgen receptor modulator)
  • API
  • 159752-10-0
  • SARMS
Mol File:
159752-10-0.mol
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MK-677 Chemical Properties

Melting point:
164-170°C
storage temp. 
2-8°C
solubility 
H2O: soluble5mg/mL, clear
form 
powder
color 
white to beige
InChIKey
DUGMCDWNXXFHDE-VZYDHVRKSA-N
SMILES
S(O)(=O)(=O)C.S(N1C2C=CC=CC=2C2(CCN(C(=O)[C@H](NC(=O)C(N)(C)C)COCC3C=CC=CC=3)CC2)C1)(=O)(=O)C |&1:19,r|
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Safety Information

WGK Germany 
3
RTECS 
TX1404490
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MK-677 Usage And Synthesis

Description

MK-677 (also known as ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

Benefits

The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies. 

Uses

Growth hormone releasing factor.MK-677 is a potent, non-peptide ghrelin receptor agonist.

Biochem/physiol Actions

It is also known as ibutamoren mesylate. MK-677 is a mimic of growth hormone (GH)-releasing peptide and is orally active.

Side effects

Reported side effects of MK-677 are typically the result of unnaturally high levels of growth hormone in the body from taking too much too often, which include:
Increased appetite
Lethargy
Joint pain if you have previous medical conditions or elevated hormone levels
Insulin resistance
Possible increase in prolactin levels, which can be controlled
When dosed properly, the side effects of MK-677 are minimal to none compared to the results you get from taking it properly. 

storage

Store at -20°C

MK-677Supplier

Hunan Fengdu Biotechnology Co., Ltd Gold
Tel
13533334465
Email
396587392@qq.com
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Email
sales@BioChemBest.com
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Email
chenyj@titansci.com
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Heterochem
Tel
027-88041443 13072715837
Email
sales@hetero-chem.com