MK-677 Chemical Properties

Melting point:

164-170°C

storage temp. 

2-8°C

solubility 

H2O: soluble5mg/mL, clear

form 

powder

color 

white to beige

InChIKey

DUGMCDWNXXFHDE-VZYDHVRKSA-N

SMILES

S(O)(=O)(=O)C.S(N1C2C=CC=CC=2C2(CCN(C(=O)[C@H](NC(=O)C(N)(C)C)COCC3C=CC=CC=3)CC2)C1)(=O)(=O)C |&1:19,r|

Safety Information

WGK Germany 

3

RTECS 

TX1404490

MK-677 Usage And Synthesis

Description

MK-677 (also known as ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

Benefits

The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies. 

Uses

Growth hormone releasing factor.MK-677 is a potent, non-peptide ghrelin receptor agonist.

Biochem/physiol Actions

It is also known as ibutamoren mesylate. MK-677 is a mimic of growth hormone (GH)-releasing peptide and is orally active.

Side effects

Reported side effects of MK-677 are typically the result of unnaturally high levels of growth hormone in the body from taking too much too often, which include:
Increased appetite
Lethargy
Joint pain if you have previous medical conditions or elevated hormone levels
Insulin resistance
Possible increase in prolactin levels, which can be controlled
When dosed properly, the side effects of MK-677 are minimal to none compared to the results you get from taking it properly. 

storage

Store at -20°C

MK-677(159752-10-0)Related Product Information

• Tricaine methanesulfonate
• Phentolamine mesilate
• Amorolfine Hydrochloride
• Testosterone propionate
• Clomiphene Citrate
• Metandienone
• 2-(4-PHENYLPIPERIDIN-1-YL)ETHANAMINE
• SPIRO[INDOLINE-3,4'-PIPERIDINE]
• N-(PIPERIDINOETHYL)ETHYLENEDIAMINE
• CHEMBRDG-BB 4011924
• CHEMBRDG-BB 4009817
• N-METHYL-N-(4-PIPERIDINYLMETHYL)-METHANESULFONAMIDE
• 2-[(2-amino-2-methyl-propyl)amino]ethanol
• MK-677