Fmoc-NH-PEG3-CH2COOH Chemical Properties

Melting point:

46℃

Boiling point:

658.9±50.0 °C(Predicted)

Density 

1.248±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Soluble in DMSO

pka

3.39±0.10(Predicted)

Safety Information

HS Code 

2942000090

Fmoc-NH-PEG3-CH2COOH Usage And Synthesis

Description

Fmoc-NH-PEG3-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

Fmoc-NH-PEG3-CH2COOH Appearance is colourless to light yellow viscous liquid, stored at -20℃.

Uses

Fmoc-9-amino-4,7-dioxanonanoic acid is an amino acid derivative and can be used as a pharmaceutical intermediate.

Fmoc-NH-PEG3-CH2COOH(139338-72-0)Related Product Information

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• FMoc-NH-PEG9-CH2CH2COOH