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Neoarsphenamine

Basic information Safety Supplier Related

Neoarsphenamine Basic information

Product Name:
Neoarsphenamine
Synonyms:
  • collunovar
  • collunover
  • miarsenol
  • neoarsfenamin
  • neoarsoluin
  • neo-i.c.i.
  • neosalvarsan
  • Sodium [[5-(3-amino-4-hydroxyphenyl)arsanylidenearsanyl-2-hydroxyphenyl]amino]methanesulfinate
CAS:
457-60-3
MF:
C13H13As2N2NaO4S
MW:
466.15
EINECS:
207-273-7
Mol File:
457-60-3.mol
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Neoarsphenamine Chemical Properties

CAS DataBase Reference
457-60-3
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
24/25-36
Toxicity
guinea pig,LDLo,intraperitoneal,75mg/kg (75mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 9, Pg. 354, 1917.
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Neoarsphenamine Usage And Synthesis

Description

Neosalvarsan (compound 914) is a salt derivative of Salvarsan and is water soluble, which showed reduced side effects .Later work showed that neither Salvarsan nor Neosalvarsan was the active pharmaceutical ingredient (API).

Uses

Treatment against syphilis.

Safety Profile

Poison by intravenous and subcutaneous routes. When heated to decomposition it emits very toxic fumes of As, , NOx, Na2O,and SOx,. See also ARSENIC COMPOUNDS.

Neoarsphenamine Preparation Products And Raw materials

Raw materials

NeoarsphenamineSupplier

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