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3-Ethynylimidazo[1,2-b]pyridazine

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3-Ethynylimidazo[1,2-b]pyridazine Basic information

Product Name:
3-Ethynylimidazo[1,2-b]pyridazine
Synonyms:
  • 3-Ethynylimidazo[1,2-b]pyridazine
  • IMidazo[1,2-b]pyridazine, 3-ethynyl-
  • Ponatinib Impurity 1
  • 3-Ethynylimidazolo[1,2-b]pyridazine
CAS:
943320-61-4
MF:
C8H5N3
MW:
143.15
Mol File:
943320-61-4.mol
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3-Ethynylimidazo[1,2-b]pyridazine Chemical Properties

Density 
1.15±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
3.71±0.30(Predicted)
form 
solid
color 
White to grey
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Safety Information

HS Code 
2933998090
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3-Ethynylimidazo[1,2-b]pyridazine Usage And Synthesis

Uses

3-Ethynylimidazo[1,2-b]pyridazine is used as an intermediate of Ponatinib, a BCR-ABL tyrosine kinase inhibitor anticancer drug used in the treatment of chronic myeloid leukaemia (CML) and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL).

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