3-Ethynylimidazo[1,2-b]pyridazine Chemical Properties

Density 

1.15±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

pka

3.71±0.30(Predicted)

form 

solid

color 

White to grey

InChI

InChI=1S/C8H5N3/c1-2-7-6-9-8-4-3-5-10-11(7)8/h1,3-6H

InChIKey

VYOHSFQVMLAURO-UHFFFAOYSA-N

SMILES

C12=NC=C(C#C)N1N=CC=C2

Safety Information

HS Code 

2933998090

3-Ethynylimidazo[1,2-b]pyridazine Usage And Synthesis

Uses

3-Ethynylimidazo[1,2-b]pyridazine is used as an intermediate of Ponatinib, a BCR-ABL tyrosine kinase inhibitor anticancer drug used in the treatment of chronic myeloid leukaemia (CML) and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL).

3-Ethynylimidazo[1,2-b]pyridazine(943320-61-4)Related Product Information

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