Meta Fluoxetine Hydrochloride
Meta Fluoxetine Hydrochloride Basic information
- Product Name:
- Meta Fluoxetine Hydrochloride
- Synonyms:
-
- Meta Fluoxetine Hydrochloride
- Fluoxetine Related CoMpound A
- N-Methyl-3-phenyl-3-[(alpha,alpha,alpha-(trifluoro-M-tolyl)oxy]propylaMine Hydrochloride
- Fluoxetine EP Impurity
- (+/-)N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride
- Fluoxetine Hydrochloride Impurity Ⅳ：N-Methyl-γ-[3-(trifluoromethyl)phenoxy]benzenepropanamine
- N-Methyl-3-phenyl-3-[(α,α,α-trifluoro-m-tolyl)oxy]propylamine
- Fluoxetine Related Compound A (15 mg) (N-methyl-3-phenyl-3-[(alpha, alpha, alpha-trifluoro-m-tolyl)oxy]propylamine hydrochloride)
- CAS:
- 79088-29-2
- MF:
- C17H19ClF3NO
- MW:
- 345.7870696
- Product Categories:
-
- Amines
- Aromatics
- Impurities
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 79088-29-2.mol
Meta Fluoxetine Hydrochloride Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMF: 16 mg/ml; DMSO: 12.5 mg/ml; Ethanol: 12.5 mg/ml; PBS (pH 7.2): 0.2 mg/ml
Meta Fluoxetine Hydrochloride Usage And Synthesis
Description
meta-Fluoxetine is an isomer of fluoxetine that is found as an impurity in fluoxetine preparations. meta-Fluoxetine is a weaker serotonin selective reuptake inhibitor (SSRI) than fluoxetine, in which the trifluoromethyl group is at the para position (Kis = 166 and 17 nM, respectively, in rat brain synaptosomes).
Chemical Properties
Off-White Solid
Uses
Fluoxetine (F597100) meta isomer. Fluoxetine impurity.
References
[1] D T WONG. A new selective inhibitor for uptake of serotonin into synaptosomes of rat brain: 3-(p-trifluoromethylphenoxy). N-methyl-3-phenylpropylamine.[J]. Journal of Pharmacology and Experimental Therapeutics, 1975, 193 3: 804-811.
[2] DAVID T. WONG Eric A E Frank P Bymaster. Prozac (fluoxetine, lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: Twenty years since its first publication[J]. Life sciences, 1995, 57 5: Pages 411-441. DOI: 10.1016/0024-3205(95)00209-o
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Meta Fluoxetine Hydrochloride(79088-29-2)Related Product Information
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