Basic information Safety Supplier Related

1-(4-chloro-3-(trifluoromethyl)phenyl)urea

Basic information Safety Supplier Related

1-(4-chloro-3-(trifluoromethyl)phenyl)urea Basic information

Product Name:
1-(4-chloro-3-(trifluoromethyl)phenyl)urea
Synonyms:
  • Sorafenib impurity N
  • 1-(4-chloro-3-(trifluoromethyl)phenyl)urea
  • N-[4-Chloro-3-(trifluoromethyl)phenyl]urea
  • Sorafenib related coMpound 9
  • Sorafenib Impurity L
  • [4-chloro-3-(trifluoromethyl)phenyl]urea
  • Sorafenib Impurity 22
  • Sorafenib impurity 8/1-(4-Chloro-3-(trifluoromethyl)phenyl)urea
CAS:
343247-69-8
MF:
C8H6ClF3N2O
MW:
238.59
Mol File:
343247-69-8.mol
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1-(4-chloro-3-(trifluoromethyl)phenyl)urea Chemical Properties

Boiling point:
275℃
Density 
1.537
Flash point:
120℃
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1-(4-chloro-3-(trifluoromethyl)phenyl)urea Usage And Synthesis

Uses

1-(4-Chloro-3-(trifluoromethyl)phenyl)urea is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.

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