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Bupivacaine Hydrochloride

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Bupivacaine Hydrochloride Basic information

Product Name:
Bupivacaine Hydrochloride
Synonyms:
  • Bupivacaine Hydrochloride (500 mg)
  • 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride hydrate
  • bupivacaine hydrochloride hydrate
  • Bupivacaine HCl hydrate
  • 1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride hydrate
  • 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, hydrochloride, hydrate (1:1:1)
  • 1-butyl-N-(2,6-dimethylphenyl)-2-Piperidinecarboxamide hydrochloride hydrate (1:1:1)
  • Bupivacaine HCl H2O IP/USP/BP/EP
CAS:
73360-54-0
MF:
C18H31ClN2O2
MW:
342.91
EINECS:
642-205-3
Product Categories:
  • API
Mol File:
73360-54-0.mol
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Bupivacaine Hydrochloride Chemical Properties

Melting point:
255-259℃
RTECS 
TK6125000
storage temp. 
room temp
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Water Solubility 
Soluble in water to 50 mM, in DMSO to 100 mM and in ethanol to 100 mM.
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Safety Information

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
22-36/37/39-45
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3
HazardClass 
6.1
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Bupivacaine Hydrochloride Usage And Synthesis

Uses

It is employed as Na+ channel blocker, local anesthetic and cAMP production inhibitor. It acts as a surfactant molecule possessing both hydrophilic and lipophilic properties, adrenergic antagonist, EC 3.1.1.8 (cholinesterase) inhibitor and EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor.

Definition

ChEBI: A racemate composed of equimolar amounts of dextrobupivacaine hydrochloride hydrate and levobupivacaine hydrochloride hydrate. A piperidinecarboxamide-based local anaesthetic, it has a slow onset and long duration of action.

Bupivacaine HydrochlorideSupplier

Nanjing Chemlin Chemical Co., Ltd
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Sinopharm Chemical Reagent Co,Ltd.
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Spectrum Chemical Manufacturing Corp.
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