Ethyl trans-2-[4-(Boc-aMino)cyclohexyl]acetate Chemical Properties

Melting point:

75 °C

Boiling point:

378.0±11.0 °C(Predicted)

Density 

1.04±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

form 

powder to crystal

pka

12.50±0.40(Predicted)

color 

White to Almost white

InChI

InChI=1S/C15H27NO4/c1-5-19-13(17)10-11-6-8-12(9-7-11)16-14(18)20-15(2,3)4/h11-12H,5-10H2,1-4H3,(H,16,18)/t11-,12-

InChIKey

GKBUJPUBSPCDGF-HAQNSBGRSA-N

SMILES

[C@@H]1(CC(OCC)=O)CC[C@@H](NC(OC(C)(C)C)=O)CC1

Safety Information

HS Code 

2924297099

Ethyl trans-2-[4-(Boc-aMino)cyclohexyl]acetate Usage And Synthesis

Uses

Ethyl 2-((1R,4R)-4-((tert-Butoxycarbonyl)amino)cyclohexyl)acetate is an intermediate for the synthesis of Desmethyl Cariprazine Hydrochloride (D291365), a derivative of Cariprazine (C183490) which is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.

Ethyl trans-2-[4-(Boc-aMino)cyclohexyl]acetate(946598-34-1)Related Product Information

• tert-Butyl (trans-4-(2-hydroxyethyl)cyclohexyl)carbamate
• 1,3-Cyclohexanebis(methylamine)
• Cyclohexylboronic acid pinacol ester
• CYCLOHEXANE-1,1-DICARBOXYLIC ACID
• Cyclohexanecarboxamide
• 1,3-Cyclohexanedicarboxylic acid
• Cyclohexanecarboxaldehyde
• Cyclohexanecarboxylic acid
• trans-4-Aminocyclohexanol
• Ethyl trans-2-(4-Aminocyclohexyl)acetate Hydrochloride