Methylophiopogonanone B CAS#: 74805-91-7

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Methylophiopogonanone B

Basic information Safety Supplier Related

Methylophiopogonanone B Basic information

Product Name:

Methylophiopogonanone B

Synonyms:

(3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-4H-1-benzopyran-4-one
Methylophiopogonanone B
NE-IV
R-Methylophiopogonanone B
Methylophiopogonanone B(R-Methylophiopogonanone B)
8-Methylophiopogonanone B
3-(4'-methoxy-benzyl)-5,7-dihydroxy-6,8-dimethyl-chroman-4-one
(3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4 H-chromen-4-one

CAS:

74805-91-7

MF:

C19H20O5

MW:

328.36

Mol File:

74805-91-7.mol

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Methylophiopogonanone B Chemical Properties

Boiling point:: 554.5±49.0 °C(Predicted)
Density: 1.285
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Soluble in acetone, chloroform and methanol;
form: powder
pka: 8.24±0.40(Predicted)
color: Light yellow
Water Solubility: insoluble in water

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Methylophiopogonanone B Usage And Synthesis

Description

Methylophiopogonanone B (MO‑B), which belongs to a group of homoisoflavonoids, present in Ophiopogon japonicus, has been identified as an active component with antioxidative and anti‑tumor properties.

Chemical Properties

Methylophiopogonanone B is soluble in methanol, ethanol, DMSO and other organic solvents, and is derived from the fibrous root of Ophiopogon japonicus.

Uses

Methylophiopogonanone B has the effect of enhancing protease activity and regulating cytoskeleton remodeling.

Synthesis

Methylophiopogonanone B was synthesized from 2,4,6-trihydroxy-3,5-dimethylacetophenone in 57% yield.

References

[1] M. FUJII. First synthesis of racemic methylophiopogonanone B and its inhibitory activity of hypoxia-inducible factor-1α[J]. Heterocycles, 2009, 78 1: 207-212. DOI:10.3987/COM-08-11517.

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