2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride CAS#: 199864-86-3

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2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride

Basic information Safety Supplier Related

2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Basic information

Product Name:

2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride

Synonyms:

2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine hydrochloride
2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
2-AMino-4-(4-fluoronaphth-1-yl)-6-isopropylpyriMidine Monohydrochloride
MT 500 Hydrochloride
4-(4-Fluoro-1-naphthyl)-6-isopropylpyriMidin-2-aMine
4-(4-Fluoro-1-naphthalenyl)-6-(1-methylethyl)-2-pyrimidinamine monohydrochloride
RS 127445 hydrochloride NEW

CAS:

199864-86-3

MF:

C17H17ClFN3

MW:

317.7883832

Mol File:

199864-86-3.mol

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2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Chemical Properties

Melting point:: 158 °C
storage temp.: 2-8°C
solubility: DMSO: ≥20mg/mL
form: powder
color: white to tan

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Safety Information

Hazard Codes: T
Risk Statements: 25-36
Safety Statements: 26-45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
HS Code: 2933.59.5300

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2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Usage And Synthesis

Uses

RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites.

storage

Desiccate at +4°C

2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, MonohydrochlorideSupplier

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