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Pamoic acid

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Pamoic acid Basic information

Product Name:
Pamoic acid
Synonyms:
  • PAMOIC ACID
  • EMBONIC ACID
  • EMBIONIC ACID
  • Pamoic
  • 2-Naphthalenecarboxylic acid, 4,4-methylenebis3-hydroxy-
  • 1,1'-methylene-bis(2-hydroxy-3-naphthoic acid)
  • PAMOIC ACID pure
  • 1,1μ-Methylene-bis(2-hydroxy-3-naphthoic acid), 4,4μ-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid
CAS:
130-85-8
MF:
C23H16O6
MW:
388.37
EINECS:
204-998-0
Product Categories:
  • Antiparasitic Agents
  • Bioactive Small Molecules
  • Biochemicals and Reagents
  • Building Blocks
  • C13 to C42+
  • Carbonyl Compounds
  • Carboxylic Acids
  • Cell Biology
  • Chemical Synthesis
  • Fatty Acids and conjugates
  • Fatty Acyls
  • Lipids
  • Organic Building Blocks
  • P
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Straight Chain Fatty Acids
Mol File:
130-85-8.mol
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Pamoic acid Chemical Properties

Melting point:
≥300 °C (dec.)
Boiling point:
434.1°C (rough estimate)
Density 
1.2472 (rough estimate)
refractive index 
1.4593 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in nitrobenzene, pyridine
form 
Crystalline Powder
pka
2.67±0.30(Predicted)
color 
Yellow to yellow-green
Water Solubility 
PRACTICALLY INSOLUBLE
Merck 
14,7005
BRN 
901319
InChIKey
WLJNZVDCPSBLRP-UHFFFAOYSA-N
CAS DataBase Reference
130-85-8(CAS DataBase Reference)
EPA Substance Registry System
2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy- (130-85-8)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-48-41-37/38-20/21/22
Safety Statements 
26-36-45-36/37/39-22
WGK Germany 
3
RTECS 
QL2180000
TSCA 
Yes
HS Code 
29182990
Toxicity
eye-rbt 100 mg MOD FCTOD7 20,573,82

MSDS

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Pamoic acid Usage And Synthesis

Chemical Properties

Pamoic acid is yellow to yellow-green crystalline powder

Uses

Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases.

Uses

Pamoic acid is used in preparation of repository derivatives of medicinal agents, used in pharmacology to increase the solubility of a drug in water.

Definition

ChEBI: Pamoic acid is a dicarboxylic acid. It is functionally related to a 2-naphthoic acid. It is a conjugate acid of a pamoate(2-).

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Safety Profile

Poison by intraperitoneal route. An eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Pamoic acid Preparation Products And Raw materials

Preparation Products

Pamoic acidSupplier

Jinan Liheng Biotechnology Co., Ltd. Gold
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