Bis-5,5-nortrachelogenin
Bis-5,5-nortrachelogenin Basic information
- Product Name:
- Bis-5,5-nortrachelogenin
- Synonyms:
-
- Bis-5,5-nortrachelogenin
- (3S,3'S,4S,4'S)-4,4'-[(6,6'-Dihydroxy-5,5'-dimethoxy[1,1'-biphenyl]-3,3'-diyl)bis(methylene)]bis[dihydro-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
- 2(3H)-Furanone, 4,4'-[(6,6'-dihydroxy-5,5'-dimethoxy[1,1'-biphenyl]-3,3'-diyl)bis(methylene)]bis[dihydro-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3S,3'S,4S,4'S)- (9CI)
- (3S,3'S,4S,4'S)-4,4'-[(6,6'-Dihydroxy-5,5'-dimethoxy[1,1'-biphenyl]-3,3'-diyl)bis(methylene)]bis[dihydro-3-hydroxy-3-[(4
- CAS:
- 870480-56-1
- MF:
- C40H42O14
- MW:
- 746.75
- Mol File:
- Mol File
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Bis-5,5-nortrachelogenin Chemical Properties
- Boiling point:
- 930.9±60.0 °C(Predicted)
- Density
- 1.430±0.06 g/cm3(Predicted)
- pka
- 9.02±0.50(Predicted)
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Bis-5,5-nortrachelogenin Usage And Synthesis
Uses
Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC50 value of 48.6 mM[1].
References
[1] Wang LY, et al. Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities. Chem Pharm Bull (Tokyo). 2005 Oct;53(10):1348-51. DOI:10.1248/cpb.53.1348
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