1-Bromo-4-iodobenzene
1-Bromo-4-iodobenzene Basic information
- Product Name:
- 1-Bromo-4-iodobenzene
- Synonyms:
-
- benzene,1-broMo-4-iodo-
- 1-BroMo-4-iodobenzene, 98% 25GR
- 1-Brom-4-iodobenzene
- 4-Bromoiodobenzene 99+%
- 4-BroMoiodobenzene, 97+%
- 4-BroMoiodoben
- The broMine iodobenzene
- 4-Bromoiodobenzene p-Bromoiodobenzene
- CAS:
- 589-87-7
- MF:
- C6H4BrI
- MW:
- 282.9
- EINECS:
- 209-662-7
- Product Categories:
-
- Building Blocks
- Chemical Synthesis
- Halogenated benzene series
- Halogenated Hydrocarbons
- Organic Building Blocks
- alkyl Iodine|alkyl bromide
- Miscellaneous
- Benzene derivates
- Bromine Compounds
- Iodine Compounds
- Light yellow crystalline powder
- Aryl
- C6
- Halogenated Hydrocarbons
- bc0001
- 589-87-7
- Mol File:
- 589-87-7.mol
1-Bromo-4-iodobenzene Chemical Properties
- Melting point:
- 89-91 °C(lit.)
- Boiling point:
- 120-122 °C14 mm Hg(lit.)
- Density
- 2.2236 (rough estimate)
- refractive index
- 1.6618 (estimate)
- Flash point:
- 120-122°C/14mm
- storage temp.
- Store below +30°C.
- solubility
- 0.008g/l
- form
- Crystalline Powder, Crystals or Needles
- color
- White to brown
- Water Solubility
- Insoluble in water.
- Sensitive
- Light Sensitive
- BRN
- 1904545
- InChIKey
- UCCUXODGPMAHRL-UHFFFAOYSA-N
- CAS DataBase Reference
- 589-87-7(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzene, 1-bromo-4-iodo-(589-87-7)
- EPA Substance Registry System
- Benzene, 1-bromo-4-iodo- (589-87-7)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- Hazard Note
- Harmful/Light Sensitive
- TSCA
- T
- HazardClass
- IRRITANT, LIGHT SENSITIVE, IRRITANT-HARMFUL
- HS Code
- 29036990
MSDS
- Language:English Provider:p-Bromoiodobenzene
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
1-Bromo-4-iodobenzene Usage And Synthesis
Synthesis methods
Industrial parabromoaniline is as raw material, by diazotization, iodo-synthesis of bromo iodobenzene. Preferred synthesis conditions: firstly 0.02mol parabromoaniline is dissolved in a mass fraction of 20% sulfuric acid medium, then reacts with 0.021molNaNO2 to generate bromophenyl diazonium sulfate at-10℃, and then chloroform and 0.021molKI is added into solution to process iodination reaction, after simple treatment bromo-iodobenzene crude product (which the bromo-iodobenzene HPLC purity 98.4%) is obtained, total yield after purification is 80%, increases by 15% than before improved. The product processes structural characterization by IR and 1HNMR. The improved method can greatly improve the purity of the crude product, this avoids the trouble of going through the column, this method is safe and easy to operate, easy to control the process, cost is lower, it is more suitable for the preparation of 1-Bromo-4-iodobenzene.
Unit: Heilongjiang University of Chemistry and Materials Science
Author: Guo Jing Bai Xuefeng Lvhong Fei
Uses
1. 1-Bromo-4-iodobenzene is used for organic synthesis.
2. Used as substrate for copper-free Sonogashira coupling reaction in aqueous acetone.
3. For the synthesis of β,β-dibromostyrene.
Chemical Properties
white to brown cryst. powder, crystals or needles
Uses
suzuki reaction
Uses
1-Bromo-4-iodobenzene has been employed:
- as reagent for in situ desilylation and coupling of silylated alkynes
- as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids)
- as substrate in copper-free Sonogashira coupling in aqueous acetone
- in synthesis of β,β,dibromostyrenes
General Description
Vapour pressure as a function of temperature for 1-bromo-4-iodobenzene has been studied using a diaphragm manometer and torsion mass-loss effusion.
1-Bromo-4-iodobenzene Preparation Products And Raw materials
Preparation Products
1-Bromo-4-iodobenzeneSupplier
- Tel
- 18300239268
- xinhuang@sddhpharm.com
- Products Intro
- Product Name:4-Bromoiodobenzene
CAS:589-87-7
Purity:99 Package:25kg
- Tel
- 025-66099280 17798518460
- cfzhang@aikonchem.com
- Products Intro
- Product Name:1-BroMo-4-iodobenzene
CAS:589-87-7
Purity:95% Package:1g;5g;10g
- Tel
- 13031698386 18753684562
- 1577399715@qq.COM
- Products Intro
- CAS:589-87-7
Purity:99% HPLC Package:1kg;5kg;10kg;25kg
- Tel
- 0536-8888106 17663601818
- 2354379876@qq.com
- Products Intro
- CAS:589-87-7
Purity:99%
- Tel
- 029-81116050 17782851193
- 168361757@qq.com
- Products Intro
- CAS:589-87-7
Purity:98% Package:100kg;50kg;5KG;1KG
1-Bromo-4-iodobenzene(589-87-7)Related Product Information
- 4-Pentylbromobenzene
- (Diacetoxyiodo)benzene
- 4-Bromobenzoic acid
- 4-Iodoanisole
- Iodobenzene
- 1,4-Diiodobenzene
- 4-Bromomethylbenzoic acid
- 4'-Bromoacetophenone
- 4-Bromobenzotrifluoride
- 4-Bromofluorobenzene
- 4-Isopropylaniline
- Methyl 4-bromobenzoate
- Ethyl 4-bromophenylacetate
- 4-Bromophenylacetic acid
- 4-Bromobenzaldehyde
- 1-Bromo-2-iodobenzene
- 1-BROMO-3-IODOBENZENE,1-Bromo-3-iodobenzene (stabilized with Copper chip),3-BROMO-1-IODOBENZENE,1-Bromo-3-iodobenzene,98%
- Bromine