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Ezetimibe Impurity

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Ezetimibe Impurity Basic information

Product Name:
Ezetimibe Impurity
Synonyms:
  • Ezetimibe Impurity I
  • Ezetimibe IMP
  • (R)-N,5-bis(4-fluorophenyl)-2-(4- hydroxybenzyl)pentanamide
  • Ezetimibe impuriry 13/(R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide
  • Ezetimibe-11
  • 3-Dehydroxy Ezetimibe Open Ring Impurity
  • Benzenepentanamide, 4-fluoro-N-(4-fluorophenyl)-α-[(4-hydroxyphenyl)methyl]-, (αR)-
  • N,5-Bis(4-fluorophenyl)-2R-(4-hydroxybenzyl)pentanamide
CAS:
1510820-22-0
MF:
C24H23F2NO2
MW:
395.45
Mol File:
1510820-22-0.mol
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Ezetimibe Impurity Chemical Properties

Boiling point:
610.4±55.0 °C(Predicted)
Density 
1.246±0.06 g/cm3(Predicted)
solubility 
Dichloromethane; DMSO; Ethyl Acetate
form 
Solid
pka
10.04±0.15(Predicted)
color 
White
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Ezetimibe Impurity Usage And Synthesis

Uses

3-Dehydroxy Ezetimibe Open Ring Impurity is an impurity in the synthesis of 3-Dehydroxy Ezetimibe, a derivative of Ezetimibe (E975000), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.

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