SP-420
SP-420 Basic information
- Product Name:
- SP-420
- Synonyms:
-
- SP-420
- (4S)-4,5-Dihydro-2-[2-hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl]-4-methyl-4-thiazolecarboxylic acid
- SP420;SP 420
- CS-2097
- 4-Thiazolecarboxylic acid, 4,5-dihydro-2-[2-hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl]-4-methyl-, (4S)-
- (2E,4S)-2-[4-[2-(2-methoxyethoxy)ethoxy]-6-oxocyclohexa-2,4-dien-1-ylidene]-4-methyl-1,3-thiazolidine-4-carboxylic acid
- SP420,SP-420,Inhibitor,inhibit
- (S)-2-(2-Hydroxy-4-(2-(2-methoxyethoxy)ethoxy)phenyl)-4-methyl-4,5-dihydrothiazole-4-carboxylic acid
- CAS:
- 911714-45-9
- MF:
- C16H21NO6S
- MW:
- 355.41
- Mol File:
- 911714-45-9.mol
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SP-420 Chemical Properties
- Melting point:
- 82-83℃ (ethyl acetate hexane )
- Boiling point:
- 562.2±60.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 10mg/mL; DMSO: 15mg/mL; Ethanol: 15mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2mg/mL
- form
- A crystalline solid
- pka
- 1.02±0.40(Predicted)
- color
- Light yellow to khaki
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SP-420 Usage And Synthesis
Description
SP 420 is an iron chelator and a derivative of desferrothiocin. It induces iron excretion in rat bile and urine with an iron-clearing efficiency (ICE) value of 26.7% when administered at a dose of 300 μmol/kg and decreases iron levels in rat liver and heart at 384 μmol/kg per day. SP 420 (75 μmol/kg) also induces iron excretion in iron-overloaded C. apella monkeys (ICE = 26.3%).
SP-420Supplier
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
Haoyuan Chemexpress Co., Ltd.
- Tel
- 021-58950125
- info@chemexpress.com
CEG Chemical Science&Technology Co., Ltd.
- Tel
- Mobile:13665161512
AdooQ Bioscience CHINA
- Tel
- 025-58849295 18951903616;
- info@adooq.cn
Credit Asia Chemical Co., Ltd.
- Tel
- +86 (21) 61124340