PSI-7976
PSI-7976 Basic information
- Product Name:
- PSI-7976
- Synonyms:
-
- PSI-7976
- N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester
- Sofosbuvir (R)-Phosphate
- (S)-isopropyl 2-((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate
- isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Lalaninate
- L-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester
- isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanite
- Sofosbuvir impurity 14/ RP-Isomer of Sofosbuvir/Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
- CAS:
- 1190308-01-0
- MF:
- C22H29FN3O9P
- MW:
- 529.45
- Mol File:
- 1190308-01-0.mol
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PSI-7976 Chemical Properties
- Melting point:
- 76-82°C
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly)
- pka
- 9.39±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
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PSI-7976 Usage And Synthesis
Uses
Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
PSI-7976Supplier
JiNan QiYuan Biotechnology Co., Ltd Gold
- Tel
- 18766124282; 18766124282
- 18766124282@163.COM
Shandong Boluoda Biological Technology Co., Ltd. Gold
- Tel
- 0531-58188909
- 3007997694@qq.com
Beijing Comparison Pharmaceutical Technology Co., Ltd
- Tel
- 010-010-52878169 15801002657
- sales@bjcomparison.com
Haoyuan Chemexpress Co., Ltd.
- Tel
- 021-58950125
- info@chemexpress.com
MedChemexpress LLC
- Tel
- 021-58955995
- sales@medchemexpress.cn
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PSI-7976(1190308-01-0)Related Product Information
- GAMMA-CYHALOTHRIN
- Sofosbuvir metabolites
- Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI)
- PSI-7977-13C-d3
- Sofosbuvir
- SofosBuvir impurity 45
- SofosBuvir Impurity 53
- sofosBuvir Impurity 37
- PSI 7411
- Sofosbuvir Impurity 6
- 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione
- Sofosbuvir Impurity27
- SofosBuvir Impurity 38
- Sofosbuvir impurity I
- (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
- Sofosbuvir impurity D
- SofosBuvir Impurity 31
- sofosBuvir Impurity 33