Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- Chemical Properties

Melting point:

>240°C (dec.)

Boiling point:

993.6±65.0 °C(Predicted)

Density 

1.423±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

DMSO (Slightly, Sonicated), Methanol (Very Slightly, Heated)

pka

13.02±0.46(Predicted)

form 

Solid

color 

White to Off-White

Major Application

pharmaceutical (small molecule)

InChIKey

RMYVVSKNFAMRGJ-UXMRNZNESA-N

SMILES

N3(C[C@@H](OC3=O)CNC(=O)NCC4OC(=O)N(C4)c5ccc(cc5)N6CCOCC6=O)c1ccc(cc1)N2CCOCC2=O

Safety Information

WGK Germany 

WGK 3

Storage Class

11 - Combustible Solids

Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- Usage And Synthesis

Uses

N,N’-Bis[Des(5-chloro-2-carvoxythienyl) Rivaroxaban] Urea is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.

Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-(1365267-35-1)Related Product Information

• Benzoic acid, 2-[[[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]aMino]carbonyl]-
• Rivaroxaban Impurity 93
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• 4-(2-nitrophenyl)Morpholin-3-one
• 4-(3-AMino-phenyl)-Morpholin-3-one
• (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione
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• (S)-2-(2-(5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)thiophene-2-carboxamido)ethoxy)acetic acid
• Rivaroxaban iMpurity
• 5-chloro-N-(4-((S)-5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)-N-(2-(2-oxo-2-((((S)-2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)amino)ethoxy)ethyl)thiophene-2-carboxamide
• Rivaroxaban iMpurity A
• 1,2-BenzenedicarboxaMide, N1,N2-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-
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• Rivaroxaban
• (S)-4,5-dichloro-N-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)thiophene-2-carboxaMide
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