2-Chlorobenzylamine Chemical Properties

Melting point:

227-228 °C(Solv: N,N-dimethylformamide (68-12-2))

Boiling point:

215 °C(lit.)

Density 

1.173 g/mL at 25 °C(lit.)

vapor pressure 

10.292Pa at 25℃

refractive index 

n20/D 1.562(lit.)

Flash point:

195 °F

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

pka

8.52±0.10(Predicted)

form 

Liquid

Specific Gravity

1.173 (20/4℃)

color 

Clear yellow

Sensitive 

Air Sensitive

BRN 

907186

InChIKey

KDDNKZCVYQDGKE-UHFFFAOYSA-N

LogP

1.6

CAS DataBase Reference

89-97-4(CAS DataBase Reference)

NIST Chemistry Reference

Benzenemethanamine, 2-chloro-(89-97-4)

EPA Substance Registry System

2-Chlorobenzylamine (89-97-4)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

36/37/38-34-37

Safety Statements 

26-36/37/39-45-36

RIDADR 

UN 2735 8/PG 2

WGK Germany 

3

F 

9-23

Hazard Note 

Irritant

TSCA 

T

HazardClass 

8

PackingGroup 

III

HS Code 

29214980

MSDS

• Language:English Provider:1-Aminomethyl-2-chlorobenzene
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Chlorobenzylamine Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

2-Chlorobenzylamine is a chlorinated derivative of benzylamine. 2-Chlorobenzylamine showed plasmin inhibitory activity as well as inhibition of bovine thrombin activity.

Synthesis Reference(s)

The Journal of Organic Chemistry, 36, p. 1710, 1971 DOI: 10.1021/jo00811a036

General Description

A colorless liquid with a slight amine odor. Somewhat soluble in water. Denser than water. Flash point 192°F. Vapors are heavier than air. Inhalation of vapors may severely irritate mucous membranes and upper respiratory tract. May severely irritate and possible burn skin. Severe eye irritant. May cause permanent damage or temporary blindness.

Air & Water Reactions

Somewhat soluble in water.

Reactivity Profile

2-CHLOROBENZYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

2-Chlorobenzylamine(89-97-4)Related Product Information

• Flunixin meglumine
• Benzylamine
• Chlorobenzene
• Trimethylamine
• Meglumine
• 2-Chlorobenzaldehyde
• 2-CHLOROBENZYLAMINE-1(THIENYL-2)-2-ETHANE HCL
• Ticlopidine hydrochloride
• Ticlopidine IMpurity G
• Benzenemethanamine, 2-chloro-N-(phenylmethylene)-, (E)- (9CI)
• 4-Oxo Ticlopidine
• Ticlopidine IMpurity J
• Ticlopidine IMpurity D
• 6.7-dihydrothieno[3.2.c]pyridin-4(5H)-one
• TICLOPIDINE IMPURITY F
• Ticlopidine IMpurity E
• thieno[3,2-c]pyridine
• 5-[(4-Chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine