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4',6'-Dinitro-2'-phenoxymethanesulfonanilide

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4',6'-Dinitro-2'-phenoxymethanesulfonanilide Basic information

Product Name:
4',6'-Dinitro-2'-phenoxymethanesulfonanilide
Synonyms:
  • 4',6'-Dinitro-2'-phenoxymethanesulfonanilide
  • N-(2,4-Dinitro-6-phenoxyphenyl)methanesulphonamide
  • N-(2,4-Dinitro-6-phenoxyphenyl)meth
  • Methanesulfonamide, N-(2,4-dinitro-6-phenoxyphenyl)-
  • N-(2,4-Dinitro-6-phenoxyphenyl)methanesulfonamide (Nimesulide Impurity)
  • NIMESULIDE EP IMP A
CAS:
51765-56-1
MF:
C13H11N3O7S
MW:
353.31
Mol File:
51765-56-1.mol
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4',6'-Dinitro-2'-phenoxymethanesulfonanilide Chemical Properties

Melting point:
155℃
Boiling point:
474.8±55.0 °C(Predicted)
Density 
1.575±0.06 g/cm3(Predicted)
solubility 
Chloroform (Slightly)
form 
Solid
pka
4.16±0.10(Predicted)
color 
Off-White to Yellow
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4',6'-Dinitro-2'-phenoxymethanesulfonanilide Usage And Synthesis

Uses

4',6'-Dinitro-2'-phenoxymethanesulfonanilide, is an impurity of the drug Nimesulide (N477500), which is an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.

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4',6'-Dinitro-2'-phenoxymethanesulfonanilide(51765-56-1)Related Product Information