Folic acid PEG DSPE Chemical Properties

storage temp. 

-20°C

form 

Solid

color 

Yellow to brown

InChIKey

ZOYJDPBUYFCOOH-UHFFFAOYSA-N

SMILES

O=C1N=C(N=C2NC=C(N=C21)CNC1C=CC(=CC=1)C(=O)NC(C(=O)O)CCC(=O)NCCOC{-}CO{+n}C(=O)NCCOP(O)(=O)OCC(COC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC)N.N

Folic acid PEG DSPE Usage And Synthesis

Uses

DSPE-PEG(5000) Folate may be used:

• in preparation of folate functionalized nanoparticles (NPs)
• in synthesis of BTPEPBI-containing nanoparticles
• in preparation of paclitaxel loaded folate modified lipid-shell and polymer-core nanoparticles (FLPNPs)

Biological Activity

Folate receptors are cellular surface markers for numerous solid tumors. DSPE-PEG-folate (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000]) incorporated into liposomes serves as a targeting ligand. Folate targeted drug delivery is useful in diagnosing and treating cancer and inflammatory diseases. Many molecules such as toxins (proteinaceous), immune stimulators and anti-cancer drugs can be delivered to folate receptor.

Folic acid PEG DSPE(1236288-25-7)Related Product Information

• DSPE-PEG-COOH
• DSPE-PEG-NHS
• DOPE-PEG-COOH
• 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
• DSPE-PEG2000-SH
• 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT)
• DPPE-MPEG 5000
• DSPE-PEG2000-FITC
• DSPE-PEG-Mal
• N-PALMITOYL-D-SPHINGOMYELIN
• L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL
• 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
• 1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
• 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
• MPEG-2000-DSPE
• 1-OLEOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
• 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[PDP(polyethylene glycol)-2000] (aMMoniuM salt)
• 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt)