Basic information Safety Supplier Related

Tris(3-hydroxypropyltriazolylMethyl)aMine 95%

Basic information Safety Supplier Related

Tris(3-hydroxypropyltriazolylMethyl)aMine 95% Basic information

Product Name:
Tris(3-hydroxypropyltriazolylMethyl)aMine 95%
Synonyms:
  • Tris(3-hydroxypropyltriazolylMethyl)aMine 95%
  • 3,3′,3′′-(4,4′,4′′-(Nitrilotris(methylene))tris(1H-1,2,3-triazole-4,1-diyl))tris(propan-1-ol)
  • THPTA
  • Tris(3-hydroxypropyltriazolylmethyl)amine
  • 4,4',4''-Nitrilotris(4-(1H-1,2,3-triazol-4-yl)butan-1-ol)
  • 3,3',3''-((4,4'4,”-nitrilotris(methylene))tris(1H-1,2,3-triazole-5,1-diyl))tris(propan-1-ol) -(THPTA)
  • Tris(3-hydroxypropyltriazolylMethyl)aMine95%
  • tris(3-hydroxypropyltriazolymethyl)amine
CAS:
760952-88-3
MF:
C18H30N10O3
MW:
434.51
Mol File:
760952-88-3.mol
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Tris(3-hydroxypropyltriazolylMethyl)aMine 95% Chemical Properties

Melting point:
331-336°C (decomposition)
Boiling point:
723.8±70.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Very Slightly)
form 
Solid
pka
14.34±0.10(Predicted)
color 
White to Off-White
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2933.99.9701
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Tris(3-hydroxypropyltriazolylMethyl)aMine 95% Usage And Synthesis

Description

THPTA is a water-soluble, very effective ligand for Cu(I)-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). It serves a dual purpose: 1) Acceleration of the CuAAC reaction by maintaining the Cu(I) oxidation state of copper sources and 2) Protection of biomolecules from oxidative damage during the labeling reaction. THPTA is a superior alternative to water-insoluble TBTA. a) J. Am. Chem. Soc. 2011, 133, 17993. b) Bioconjugate Chem. 2010, 21, 1912.

Uses

Tris(3-hydroxypropyltriazolylmethyl)amine when complexed to copper(I) can be used as a catalyst.

storage

Store at -20°C

Tris(3-hydroxypropyltriazolylMethyl)aMine 95%Supplier

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd Gold
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0431-80514535 19917294565
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caoy@chemextension.com
Xi'an Confluore Biological Technology Co., Ltd. Gold
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+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
TCI (Shanghai) Development Co., Ltd.
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021-67121386
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Sales-CN@TCIchemicals.com
Energy Chemical
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021-021-58432009 400-005-6266
Email
sales8178@energy-chemical.com
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Email
info@chemlin.com.cn
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