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Eupaglehnin C

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Eupaglehnin C Basic information

Product Name:
Eupaglehnin C
Synonyms:
  • Eupaglehnin C
  • [(3aR,4R,6Z,10E,11aR)-6,10-dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (Z)-2-(hydroxymethyl)but-2-enoate
  • 2-Butenoic acid, 2-(hydroxymethyl)-, (3aR,4R,6E,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2Z)-
CAS:
476630-49-6
MF:
C20H26O5
MW:
346.42
Mol File:
476630-49-6.mol
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Eupaglehnin C Chemical Properties

Boiling point:
528.7±50.0 °C(Predicted)
Density 
1.15±0.1 g/cm3(Predicted)
pka
13.53±0.10(Predicted)
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Eupaglehnin C Usage And Synthesis

Uses

Eupaglehnin C is a germacrane-type sesquiterpenoi. Eupaglehnin C can be isolated from the MeOH extract of Eupatorium glehni (Compositae). Eupaglehnin C has cytotoxic activity against HeLa-S3 cancer cell lines[1][2].

References

[1] Tori M, et al. Seven germacranolides, eupaglehnins A, B, C, D, E, and F, and 2alpha-acetoxyepitulipinolide from Eupatorium glehni. Chem Pharm Bull (Tokyo). 2002 Sep;50(9):1250-4. DOI:10.1248/cpb.50.1250
[2] Zhang ML, et al. Chemical constituents of plants from the genus Eupatorium. Chem Biodivers. 2008 Jan;5(1):40-55. DOI:10.1002/cbdv.200890014

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