ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Boric acid > 4-Trifluoromethoxyphenylboronic acid
4-Trifluoromethoxyphenylboronic acid
4-Trifluoromethoxyphenylboronic acid Basic information
- Product Name:
- 4-Trifluoromethoxyphenylboronic acid
- Synonyms:
-
- AKOS BRN-0136
- 4-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID
- 4-(TRIFLUOROMETHOXY)BENZENEBORONIC ACID
- P-TRIFLUOROMETHOXY BENZOBORIC ACID
- P-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID
- RARECHEM AH PB 0078
- 4-(Trifluoromethoxy)phenylboronicAcid(containsvaryingamountsofAnhydride)
- 4-Trifluoromethoxyphenylboronic acid 4-(Trifluoromethoxy)benzeneboronic acid
- CAS:
- 139301-27-2
- MF:
- C7H6BF3O3
- MW:
- 205.93
- EINECS:
- 000-000-0
- Product Categories:
-
- Aryl
- Fluorinated
- Organoborons
- B (Classes of Boron Compounds)
- Boronic Acids
- Building Blocks for Liquid Crystals
- Substituted Boronic Acids
- Boronic Acid
- Chalcones, etc. (Building Blocks for Liquid Crystals)
- Functional Materials
- Boronic Acids
- Boronic Acids and Derivatives
- Boronate Ester
- Potassium Trifluoroborate
- blocks
- BoronicAcids
- FluoroCompounds
- Boronic Acid series
- bc0001
- Mol File:
- 139301-27-2.mol
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4-Trifluoromethoxyphenylboronic acid Chemical Properties
- Melting point:
- 123-127 °C(lit.)
- Boiling point:
- 256.6±50.0 °C(Predicted)
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- pka
- 8.29±0.10(Predicted)
- form
- Crystalline Powder
- color
- White to beige
- BRN
- 8548201
- InChIKey
- HUOFUOCSQCYFPW-UHFFFAOYSA-N
- CAS DataBase Reference
- 139301-27-2(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 37/39-26-36
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 29319090
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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4-Trifluoromethoxyphenylboronic acid Usage And Synthesis
Chemical Properties
white to beige crystalline powder
Uses
B-[4-(Trifluoromethoxy)phenyl]boronic Acid is a reagent used in the synthesis of orally bioavailable matrix metalloprotinase inhibitors. Also used in the preparation of chromen-4-one inhibitors used against DNA dependant protein kinases.
Application
4-Trifluoromethoxyphenylboronic acid can reactant involved in the synthesis of biologically active molecules including:
Lactate dehydrogenase inhibitors for use against cancer cell proliferation
Nitro-phenoxybenzoic acid derivatives for PAI-1 inhibition
PA-824 analogs for use as antituberculosis drugs
Modulators of survival motor neuron protein
Reactant involved in addition reactions and cross-coupling reactions including Suzuki-Miyaura cross-coupling
4-Trifluoromethoxyphenylboronic acidSupplier
J & K SCIENTIFIC LTD.
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- 021-67121386
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4-Trifluoromethoxyphenylboronic acid(139301-27-2)Related Product Information
- Anisole
- 4-(Trifluoromethoxy)chlorobenzene
- p-Trifluoromethoxy phenol
- 4'-(Trifluoromethoxy)acetophenone
- (4-METHOXYPHENYL)-BORANE
- 2-(Trifluoromethoxy)aniline
- (Trifluoromethoxy)benzene
- p-Anisaldehyde
- 4-Trifluoromethylphenylboronic acid
- 4-Methoxybenzoyl chloride
- 4-(Trifluoromethoxy)aniline
- 4-Methoxybenzoic acid
- 4-Methoxybenzyl cyanide
- 4'-Methoxyacetophenone
- 4-(Trifluoromethoxy)benzaldehyde
- 4-Methoxybenzyl alcohol
- 2-METHOXY-4-(TRIFLUOROMETHOXY)-PHENYLBORONIC ACID
- 2-Chloro-5-(trifluoromethyl)phenylboronic acid