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L-4-Chlorophenylalanine

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L-4-Chlorophenylalanine Basic information

Product Name:
L-4-Chlorophenylalanine
Synonyms:
  • 3-(4-Chlorophenyl)-L-alanine
  • (2R)-2-amino-3-(4-chlorophenyl)propanoic acid
  • 4-CHLORO-L-PHE-OH.HCL
  • 4-Chloro-L-phenylalanine99+%
  • P-CHLORO-PHENYLALANINE
  • P-CHLORO-L-PHENYLALANINE
  • RARECHEM BK PT 0013
  • (S)-2-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID
CAS:
14173-39-8
MF:
C9H10ClNO2
MW:
199.63
EINECS:
238-023-5
Product Categories:
  • Phenylalanine analogs and other aromatic alpha amino acids
  • Amino Acids
  • Phenylalanine [Phe, F]
  • Unusual Amino Acids
  • a-amino
Mol File:
14173-39-8.mol
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L-4-Chlorophenylalanine Chemical Properties

Melting point:
263 °C (dec.)(lit.)
alpha 
-27 º (c=0.5, H2O 34 ºC)
Boiling point:
339.5±32.0 °C(Predicted)
Density 
1.2409 (rough estimate)
refractive index 
1.5790 (estimate)
storage temp. 
-20°C
solubility 
Aqueous Base (Slightly), Water (Slightly)
form 
Powder
pka
2.18±0.10(Predicted)
color 
White
Water Solubility 
Soluble in acetic acid. Slightly soluble in water.
BRN 
2416150
InChIKey
NIGWMJHCCYYCSF-QMMMGPOBSA-N
CAS DataBase Reference
14173-39-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T,Xi
Risk Statements 
25-43
Safety Statements 
36/37-45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
HS Code 
29224999

MSDS

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L-4-Chlorophenylalanine Usage And Synthesis

Chemical Properties

white powder

Uses

4-Chloro-L-phenylalanine is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals.

Definition

ChEBI: A non-proteinogenic L-alpha-amino acid that is L-phenylalanine in which the meta-hydrogen of the phenyl group has been replaced by a chlorine.

Biochem/physiol Actions

4-Chloro-L-phenylalanine (L-PCPA) inhibits the synthesis of 5-hydroxytryptamine (5-HT). 4-Chloro-DL-phenylalanine (PCPA) depletes the serotonin levels in the brain by its inhibitory effect on tryptophan hydroxylase (Tph). Studies support the protective effects of PCPA against monocrotaline-induced pulmonary vascular remodeling as well as in lung inflammation.

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