6,7-Dimethoxy-3,4-dihydroquinazoline-4-one Chemical Properties

Melting point:

309-311°C

Boiling point:

374.1±52.0 °C(Predicted)

Density 

1.33±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly, Heated), Methanol (Slightly)

form 

Solid

pka

1.46±0.20(Predicted)

color 

Pale Beige

InChI

InChI=1S/C10H10N2O3/c1-14-8-3-6-7(4-9(8)15-2)11-5-12-10(6)13/h3-5H,1-2H3,(H,11,12,13)

InChIKey

DMSRMHGCZUXCMJ-UHFFFAOYSA-N

SMILES

N1C2=C(C=C(OC)C(OC)=C2)C(=O)NC=1

CAS DataBase Reference

13794-72-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-37/39-25-24

HazardClass 

IRRITANT

HS Code 

29334900

6,7-Dimethoxy-3,4-dihydroquinazoline-4-one Usage And Synthesis

Description

6,7-Dimethoxy-3,4-dihydroquinazoline-4-one is a white to near-white powder to crystals that is a by-product of the gefitinib manufacturing process and is a gefitinib impurity. It can be used as standard reagent or organic synthesis reagent.

Chemical Properties

White solid

Uses

Gefitinib intermediate.

6,7-Dimethoxy-3,4-dihydroquinazoline-4-one(13794-72-4)Related Product Information

• 4-(3-Chloropropyl)morpholine
• Gefitinib-d6
• Gefitinib Impurity 11
• Gefitinib Chloro Impurity
• 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
• 2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile
• Gefitinib Impurity 8
• 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
• Gefitinib 3,4-Difluoro Impurity HCl
• N-(3-chloro-4-fluorophenyl)-7 -methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine
• 3,4-Dichloroaniline
• 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
• 2-aMino-4-Methoxy-5-(3-Morpholinopropoxy)benzaMide
• 3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib
• 3-Hydroxy-4-methoxybenzonitrile
• Gefitinib Impurity 7
• 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate
• Gefitinib N-Oxide