6-Amino-2-naphthalenesulfonic acid Chemical Properties

Density 

1.3588 (rough estimate)

vapor pressure 

0Pa at 25℃

refractive index 

1.6500 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

form 

powder to crystal

pka

-0.08±0.40(Predicted)

color 

White to Light yellow to Light orange

Water Solubility 

0.12g/L(20 ºC)

InChIKey

SEMRCUIXRUXGJX-UHFFFAOYSA-N

LogP

0.603 at 25℃

CAS DataBase Reference

93-00-5(CAS DataBase Reference)

EPA Substance Registry System

6-Amino-2-naphthalenesulfonic acid (93-00-5)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HS Code 

2930909899

MSDS

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6-Amino-2-naphthalenesulfonic acid Usage And Synthesis

Description

2-Aminonaphthalene-6-sulfonic acid [93- 00-5]. (6-aminonaphthalene-2-sulfonic acid), Bronner acid, C10H9NO3S, Mr 223.24, crystallizes from water as the monohydrate in plates although only 0.2 % soluble at 100℃. Sulfonation with 20 % oleum at 20℃ gives a mixture of 1,6- and 6,8-disulfonic acids.

Uses

6-Amino-2-naphthalenesulfonic Acid is used in the synthesis of diaryl urea derivatives bearing sulfonamide moiety with an in vitro antitumor activity.

Definition

ChEBI: 6-aminonaphthalene-2-sulfonic acid is an aminonaphthalenesulfonic acid.

Production Methods

2-Hydroxynaphthalene-6-sulfonic acid is aminated by a Bucherer reaction under conditions similar to those used for Tobias acid.

Flammability and Explosibility

Not classified

Purification Methods

Crystallise the acid from a large volume of hot water. The diethylamine salt has m 190.5-192o (from EtOH/isoBuOH), and the S-benzylisothiuronium salt has m 330o (from nBuOH). [Beilstein 14 H 760, 14 II 463, 14 III 2249, 14 IV 2804.]

6-Amino-2-naphthalenesulfonic acid(93-00-5)Related Product Information

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• 2-Naphthylamine
• p-Toluenesulfonic acid
• 1-Naphthylamine
• Taurine
• Sulfamic acid
• Glycine
• Benzenesulfonic acid
• 1-DODECANESULFONIC ACID SODIUM SALT
• PHENOLDISULFONIC ACID
• Chlorosulfonic acid
• Mordant Blue 13
• SPADNS
• ARSENAZO III DISODIUM SALT
• disodium 5-((4-acetylamino-2-sulphophenyl)azo)-6-amino-4-hydroxynaphthalene-2-disulphonate
• CHROMOTROPE 2R
• ACID RED 1
• Trypan Blue